Results 171 to 180 of about 2,580 (202)

Ultrastructural Features of NUT Midline Carcinoma

Ultrastructural Pathology, 2012
Midline carcinomas associated with the nuclear protein in testis (NUT) gene rearrangement are rare, aggressive tumors that have been diagnosed most commonly in the head, neck, mediastinum, and upper aerodigestive tract. The ultrastructural features associated with this tumor have thus far received only brief comment and have never been illustrated. The
Eric P, Wartchow, Timothy S, Moore, Christopher A, French, Gary W, Mierau   +3 more
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Orbital Involvement by NUT Midline Carcinoma

Ophthalmic Plastic & Reconstructive Surgery, 2015
A 32-year-old female presented with a sino-orbital lesion that proved to be a NUT midline carcinoma. This is only the third case of orbital involvement by this aggressive lesion. The clinical, radiographic, and histopathologic features of NUT midline carcinoma are discussed, as well as its management options.
Jill N, D'Souza, Gregory, Notz, Ronald N, Bogdasarian, David M, Cognetti, Joseph M, Curry, Marc R, Rosen, Madalina, Tuluc, James J, Evans, Jurij R, Bilyk   +8 more
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NUT Midline Carcinoma

International Journal of Surgical Pathology, 2009
NUT midline carcinoma (NMC) is a recently described, undifferentiated carcinoma with specific NUT gene rearrangement, which often involves midline organs such as the nasal cavity, paranasal sinuses, mediastinum, or intrathoracic organs. It was previously considered a disease of children or young adults, but middle-aged or elderly patients have ...
Min-Shu, Hsieh, Christopher A, French, Cher-Wei, Liang, Cheng-Hsiang, Hsiao   +3 more
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NUT Midline Carcinoma

American Journal of Surgical Pathology, 2012
In this study, we report 2 pediatric cases of nuclear protein of the testis (NUT) midline carcinoma (NMC) suggestive of pulmonary origin: case 1 was a 14-year-old Japanese boy and case 2 was a 7-year-old Japanese girl. Initial symptoms of both cases were prolonged cough and chest pain, and the case 2 patient also complained of lumbago and lumbar mass ...
Mio, Tanaka, Keisuke, Kato, Kiyoshi, Gomi, Mariko, Yoshida, Tetsu, Niwa, Noriko, Aida, Hisato, Kigasawa, Yokatsu, Ohama, Yukichi, Tanaka   +8 more
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The cytologic features of NUT midline carcinoma

Cancer Cytopathology, 2009
AbstractBACKGROUND:Nuclear protein in testis (NUT) midline carcinoma (NMC) represents an aggressive, high‐grade carcinoma typically involving the upper aerodigestive tract or mediastinum. Although the tumor was originally noted in young persons, we have subsequently identified 5 adult cases.
Andrew M, Bellizzi, Cynthia, Bruzzi, Christopher A, French, Edward B, Stelow   +3 more
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Uncommon Somatic Mutations in Metastatic NUT Midline Carcinoma

Tumori Journal, 2017
Introduction NUT midline carcinoma (NMC) is a rare and aggressive epithelial cancer arising from median organs. It is driven by chromosomal translocation t(15;19) involving the rearrangement of NUT (nuclear protein in testis) and BRD4 (bromodomain 4) genes leading to fusion oncoprotein BRD4-NUT.
Cavalieri, Stathis, Anastasios, Fabbri, Alessandra, Sonzogni, Angelica, Perrone, Federica, Tamborini, Elena, Elena; Pelosi, Giuseppe; de Braud, Platania, Marco   +8 more
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The Gross Appearance of a NUT Midline Carcinoma

International Journal of Surgical Pathology, 2015
The NUT midline carcinoma (NMC) is a recently described and highly aggressive tumor that usually involves the head and neck and anterior mediastinum. Most patients with NMC present with metastases and are often treated with neoadjuvant chemotherapy and/or radiation therapy.
Jason K, Wasserman, Bibianna, Purgina, Harmanjatinder, Sekhon, Marcio M, Gomes, Chi, Lai   +4 more
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Histone deacetylase inhibitor for NUT midline carcinoma.

Pediatric blood & cancer, 2015
NUT Midline carcinoma (NMC) is a rare and invariably fatal poorly differentiated carcinoma characterized by chromosomal rearrangement involving the nuclear protein of the testis (NUT) gene. Current approaches do not provide durable response. We report a case of widely metastatic NMC in a 17-year-old female who, following an initial response to ...
Ossama M, Maher, Anthony M, Christensen, Sireesha, Yedururi, Diana, Bell, Nidale, Tarek   +4 more
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FDG PET/CT Imaging of NUT Midline Carcinoma

Clinical Nuclear Medicine, 2011
Abstract:NUT midline carcinoma is a very rare, poorly differentiated, highly aggressive cancer originating from midline body locations, most often in adolescents or young adults. Advanced local disease and distant hematogenous metastases are typical.
Ryan D, Niederkohr, Michael J, Cameron, Christopher A, French   +2 more
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NUTMidline Carcinoma in a Young Woman

Journal of Clinical Oncology, 2011
Leinster
Teo, MinYuen, Crotty, Paul, O'Sullivan, Maureen, French, Christopher A, Walshe, Janice M   +4 more
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