Results 151 to 160 of about 1,053,787 (318)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

A New Insight into the Threshold and Oscillatory Regimes in Plant-Pathogen Models: A Nutrient-Driven Approach. [PDF]

Bull Math Biol
Damay DP, Peace A.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Genomic-to-space measurements reveal large-scale ocean nutrient stress. [PDF]

Sci Adv
Martiny AC, Ustick LJ, Westberry TK, Behrenfeld MJ.   +3 more
europepmc   +1 more source

Variability in nutrient loading to lake ecosystems and associated impacts on water quality

, 2013
Globally, the accelerated eutrophication of lake ecosystems due to excess inputs of nitrogen (N) and phosphorus (P) is a significant problem. The rate of loading of N and P to lakes varies both in space and time; consequently, developing good ...
Abell, Jonathan Michael
core  

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Applications and mechanisms of biochar-mycorrhizal synergies in agriculture based on systematic review. [PDF]

PeerJ
Setyawan HY, Widyastuti E, Sugiarto Y, Sunyoto NMS, Ulandari D, Dewi J, Choirun AU, Arwani M, Okoye C.   +8 more
europepmc   +1 more source

Urban nutrient balance for Bankok

, 2001
To enhance agricultural sustainability, former linkages between agriculture and urban waste production should be reintroduced. Therefore, to explore the options for recycling of nutrients from mega-cities, a nutrient balance model was developed.
Magid, Jakob, Færge, Jens, de Vries, Fritz Pennig   +2 more
core