Results 71 to 80 of about 1,911,039 (313)

Identification of key regulators for the development of Prunus leaves using single-cell RNA sequencing

open access: yesBMC Plant Biology
Background Leaves require the coordinated regulation of multiple types of cells to accumulate energy for plants. Transcriptome analysis at the tissue level cannot analyze the heterogeneity of cells or reveal the molecular regulatory mechanisms of ...
Miao Li   +6 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The Effects of Tidal Forcing on Nutrient Fluxes in the Tidal, Freshwater James River Estuary, VA [PDF]

open access: yes, 2016
A 12-month study (January to December 2015) focused on the effects of tidal forcing on nutrient fluxes in the tidal, freshwater segment of the James River Estuary (JRE). Discrete sampling of nutrient chemistry and continuous monitoring of tidal discharge
Devore, Dana L
core   +1 more source

Dietary Diversity Score: A Measure of Nutritional Adequacy or an Indicator of Healthy Diet? [PDF]

open access: yes, 2016
At the time when the lack of indicators seemed to constrain appropriate child feeding in developing countries, dietary diversity score (DDS) emerged as a measure of nutritional adequacy that could close the gap.
Habte, Tsige-Yohannes   +1 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Fertility building strategies during the conversion period – assessment of performance in a stockless field vegetable rotation [PDF]

open access: yes, 2002
This report was presented at the UK Organic Research 2002 Conference of the Colloquium of Organic Researchers (COR). Nutrient off-takes, residue returns and nutrient inputs were measured during and after conversion from a conventional arable system to ...
Harlock, Simon   +2 more
core  

A review of farm-scale nutrient budgets for organic farms as a tool for management of soil fertility [PDF]

open access: yes, 2002
On organic farms, where the importation of materials to build/maintain soil fertility is restricted, it is important that a balance between inputs and outputs of nutrients is achieved to ensure both short-term productivity and long-term sustainability ...
Aarts   +65 more
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Microbiology Combined with the Root Metabolome Reveals the Responses of Root Microorganisms to Maize Cultivars under Different Forms of Nitrogen Supply

open access: yesAgronomy
Plant–microbe interactions are key to nutrient-use efficiency. Root microbes are influenced by rhizosphere soil and plant cultivars. The impact of cultivar-by-nitrogen (N) interactions on the maize-root microbiome remains unclear, yet it is crucial for ...
Guan Tian   +7 more
doaj   +1 more source

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