Results 71 to 80 of about 1,885,929 (310)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Metabolomics Analysis of Phenolic Composition and Content in Five Pear Cultivars Leaves
PlantsPhenolic compounds are the predominant chemical constituents in the secondary metabolites of plants and are commonly found in pears. In this study, we focused on the analysis of the phenolic composition and antioxidant activity of leaves from five pear ...
Huijun Jiao +6 more
doaj +1 more source
Decomposition of coarse woody debris in a long-term litter manipulation experiment: A focus on nutrient availability [PDF]
, 2018 The majority of above-ground carbon in tropical forests is stored in wood, which is returned to the atmosphere during decomposition of coarse woody debris.
Gora, Evan M. +3 more
core +3 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Rates of sustainable forest harvest depend on rotation length and weathering of soil minerals [PDF]
, 2014 Removals of forest biomass in the northeastern US may intensify over the coming decades due to increased demand for renewable energy. For forests to regenerate successfully following intensified harvests, the nutrients removed from the ecosystem in the ...
Blum, Joel D. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A review of farm-scale nutrient budgets for organic farms as a tool for management of soil fertility [PDF]
, 2002 On organic farms, where the importation of materials to build/maintain soil fertility is restricted, it is important that a balance between inputs and outputs of nutrients is achieved to ensure both short-term productivity and long-term sustainability ...
Aarts +65 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Derivation of a dual porosity model for the uptake of nutrients by root hairs [PDF]
, 2010 Root hairs are thought to play an important role in mediating nutrient uptake by plants. We develop a mathematical model for the nutrient transport and uptake in the root hair zone of a single root in the soil.
Roose, Tiina, Zygalakis, K. C.
core
N, P and K budgets for crop rotations on nine organic farms in the UK [PDF]
, 2003 On organic farms, where the importation of materials to build/maintain soil fertility is restricted, it is important that a balance between inputs and outputs of nutrients is achieved to ensure both short-term productivity and long-term sustainability ...
Berry, P.M. +7 more
core +1 more source