Results 81 to 90 of about 1,885,929 (310)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Comparative analysis of conventional and organic farming systems: Nitrogen surpluses and nitrogen losses [PDF]
, 2008 Nutrient management is a key factor for both economic viability and environmental performance of farming systems. On 32 representative conventional and organic farms in Northern Germany, nutrient management was analyzed in the interdisciplinary ...
Kelm, Dr. Michael +2 more
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Microalgae for municipal wastewater nutrient remediation: mechanisms, reactors and outlook for tertiary treatment [PDF]
, 2015 This review explores the use of microalgae for nutrient removal in municipal wastewater treatment, considering recent improvements in the understanding of removal mechanisms and developments of both suspended and non-suspended systems.
Bogan R +13 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Do nutrient uptakes and grain yields differ between spring barley varieties grown for organic farming as mono-crop and in mixture: Characteristics of spring barley varieties for organic farming [PDF]
, 2004 Manure application increased yield. Hence the study was conducted under the conditions of moderate nutrient stress and in all probability nitrogen stress. Under this condition nutrient uptakes, biomass production and grain yields did vary between Otira,
Berntsen, Senior Scientist J. +2 more
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Food Chemistry: XClimate change significantly impacts tea plant (Camellia sinensis) physiology, particularly the cuticular wax layer on leaves, which serves as a critical barrier against environmental stress.
Dandan Qi +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
AgronomyImproving apple peel color has been an important objective in apple production. To better understand the effect and mechanism of the combined application of urea and FA (fulvic acid) regulation of anthocyanin biosynthesis, a field experiment was ...
Laiping Wang +4 more
doaj +1 more source