Results 101 to 110 of about 386,337 (300)

Exploring plant-microbe interactions in adapting to abiotic stress under climate change: a review

Frontiers in Plant Science
Climatic change and extreme weather events have become a major threat to global agricultural productivity. Plants coexist with microorganisms, which play a significant role in influencing their growth and functional traits.
Ali Muhammad, Ali Muhammad, Xiangjun Kong, Shuaichao Zheng, Na Bai, Lijie Li, Muhammad Hafeez Ullah Khan, Sajid Fiaz, Zhiyong Zhang   +8 more
doaj   +1 more source

Receptor uptake arrays for vitamin B12, siderophores and glycans shape bacterial communities

, 2017
Molecular variants of vitamin B12, siderophores and glycans occur. To take up variant forms, bacteria may express an array of receptors. The gut microbe Bacteroides thetaiotaomicron has three different receptors to take up variants of vitamin B12 and 88 ...
Frank, Steven A.
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Nitrogen forms affect root structure and water uptake in the hybrid poplar [PDF]

, 2011
The study analyses the effects of two different forms of nitrogen fertilisation (nitrate and ammonium) on root structure and water uptake of two hybrid poplar (Populus maximowiczii x P. balsamifera) clones in a field experiment.
A Clemensson-Lindell, A Hodge, A Karacic, AH Fitter, AH Fitter, B Huang, C Glynn, CC Kern, Christian Messier, D Guo, DA Rose, DI Dickmann, DM Eissenstat, DM Eissenstat, E Salas, F Ripullone, Frank Berninger, GA Bauer, GB West, H Coners, H Ozier-Lafontaine, H Poorter, HP Harvey, HP Harvey, J Lopez-Bucio, J Lynch, JA Parkinson, JEK Cooke, JS King, JS King, KS Pregitzer, KS Pregitzer, KS Pregitzer, L Coll, Lluís Coll, M Noordwijk van, MD Coleman, P Armengaud, R Driesche Van den, R Fujimaki, RMA Block, S Delagrange, Susy Domenicano, T Ericsson, T Sakuratani, TJ Albaugh, WTM Woolfolk, X Min   +47 more
core   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Physical and Functional Constraints on Viable Belowground Acquisition Strategies

Frontiers in Plant Science, 2019
Since their emergence onto land, terrestrial plants have developed diverse strategies to acquire soil resources. However, we lack a framework that adequately captures how these strategies vary among species.
M. Luke McCormack, Colleen M. Iversen
doaj   +1 more source

Frequency Distributions of Median Nutrient and Chlorophyll Concentrations across the Red River Basin, 1996-2006 [PDF]

, 2009
Acquisition and compilation of water quality data for a ten year time period (1996 – 2006) from 589 stream and river stations was conducted to support nutrient criteria development for the multi–state Red River Basin shared by Arkansas, Louisiana, New ...
Haggard, B.E., Longing, S.D.
core   +2 more sources

Nutrient acquisition by pathogenic fungi: Nutrient availability, pathway regulation, and differences in substrate utilization

International Journal of Medical Microbiology, 2011
All pathogenic microorganisms have in common that they need to feed on nutrients available from their host. Therefore, the specific interruption of metabolic pathways is a promising approach which could lead to the discovery of new antimicrobial drugs.
Christian B, Fleck, Felicitas, Schöbel, Matthias, Brock   +2 more
openaire   +2 more sources