Results 131 to 140 of about 3,075,999 (346)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Long-Term Green Manure Rotations Improve Soil Biochemical Properties, Yield Sustainability and Nutrient Balances in Acidic Paddy Soil under a Rice-Based Cropping System

open access: yesAgronomy, 2019
Cultivation of green manure (GM) crops in intensive cropping systems is important for enhancing crop productivity through soil quality improvement. We investigated yield sustainability, nutrient stocks, nutrient balances and enzyme activities affected by
Muhammad Qaswar   +11 more
doaj   +1 more source

Evaluation of Resource Management Options for Smallholder Farms Using an Integrated Modelling Approach [PDF]

open access: yes
Farm-level analysis of trade-offs between soil fertility management alternatives is required to improve understanding of complex biophysical and socio-economic factors influencing decision making in smallholder farming systems and to identify ...
Delve, Robert J.   +6 more
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Nutrient budgeting for trace elements: Examples from Scottish organic farms [PDF]

open access: yes, 2002
This report was presented at the UK Organic Research 2002 Conference. Farmgate nutrient budgets have been calculated for Cu, Co and Mo for six farms in NE Scotland.
Owens, Katie, Watson, Christine
core  

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

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