The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Cultivation of green manure (GM) crops in intensive cropping systems is important for enhancing crop productivity through soil quality improvement. We investigated yield sustainability, nutrient stocks, nutrient balances and enzyme activities affected by
Muhammad Qaswar +11 more
doaj +1 more source
Evaluation of Resource Management Options for Smallholder Farms Using an Integrated Modelling Approach [PDF]
Farm-level analysis of trade-offs between soil fertility management alternatives is required to improve understanding of complex biophysical and socio-economic factors influencing decision making in smallholder farming systems and to identify ...
Delve, Robert J. +6 more
core +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Grazing exclusion is more beneficial for restoring soil organic carbon and nutrient balance than afforestation on degraded sandy land. [PDF]
Cao W, Li Y, Chen Y, Wang X.
europepmc +1 more source
Nutrient budgeting for trace elements: Examples from Scottish organic farms [PDF]
This report was presented at the UK Organic Research 2002 Conference. Farmgate nutrient budgets have been calculated for Cu, Co and Mo for six farms in NE Scotland.
Owens, Katie, Watson, Christine
core
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Quantification of soil nutrient balance and stock on smallholder farms at Agew Mariam watershed in northern Ethiopia. [PDF]
Esubalew T, Amare T, Molla E.
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Normalized difference vegetation index sensor-based nitrogen management in bread wheat (Triticum aestivum L.): Nutrient uptake, use efficiency, and partial nutrient balance. [PDF]
Mitra B +7 more
europepmc +1 more source

