Results 41 to 50 of about 72,991 (261)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
The cultivation of leafy vegetables on metal contaminated soil embodies a serious threat to yield and quality. In the present study, the potential role of exogenous jasmonic acid (JA; 0, 5, 10, and 20 µM) on mitigating chromium toxicity (Cr; 0, 150, and ...
Muhammad Kamran +11 more
doaj +1 more source
Nutrient Cycling in Aquaponics Systems [PDF]
AbstractIn aquaponics, nutrients originate mainly from the fish feed and water inputs in the system. A substantial part of the feed is ingested by the fish and either used for growth and metabolism or excreted as soluble and solid faeces, while the rest of any uneaten feed decays in the tanks.
Eck, Mathilde +2 more
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Dependence of Metolachlor Adsorption by Biochar on Soil Properties in South China
Sorption is the most important process influencing the amount of herbicide retained in soils. The special properties of biochar could influence the soil retention of pollutants through adsorption.
Lan Wei +6 more
doaj +1 more source
Effect of iron oxide on nitrification in two agricultural soils with different pH [PDF]
Iron (Fe) affects soil nitrogen (N) cycling processes both in anoxic and oxic environments. The role of Fe in soil N transformations including nitrification, mineralization, and immobilization, is influenced by redox activity, which is regulated by soil ...
X. Huang +6 more
doaj +1 more source
Biogeochemical nutrient cycles and nutrient management strategies [PDF]
Nutrient loading by riverine input into estuarine systems has increased by 6–50 times for the N load from pristine conditions to present, whereas a 18–180 times increase has been observed in the P load. Reductions in the ratio of N to P delivery has also occurred with time.
openaire +2 more sources

