FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
The role of hen body weight and diet nutrient density in an extended laying cycle. [PDF]
Poult Sci, 2023 Muir WI, Akter Y, Bruerton K, Groves PJ.
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Effects of low-carbohydrate, high-nutrient-density diet combined with aerobic exercise on mental health and glycolipid metabolism in obese children and adolescents. [PDF]
Front Med (Lausanne)Li L, Zhang P, Liu X, Wang C.
europepmc +1 more source
Effect of feed form and nutrient density on growth performance, blood parameters, and intestinal traits in broiler breeder pullets. [PDF]
Poult Sci, 2023 Amoozmehr A +4 more
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Interactions of dietary nutrient density with genotype and sex in broiler chickens: implications for growth, carcass quality, and nutrient utilization. [PDF]
Poult SciXie C, Macelline S, Liu S, Toghyani M.
europepmc +1 more source
The Nutrient Rich Food Price Index: a nutrition-relevant adaptation of the Laspeyres price index to track the cost of affordable nutrient density. [PDF]
Front Nutr, 2023 Mendoza-Velázquez A +3 more
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
An Updated Definition of "Healthy" Foods in the United States: How Do They Measure in Nutrient Density, Cost, and Frequency of Consumption? [PDF]
Curr Dev NutrHooker K, Sanjeevi N, Monsivais P.
europepmc +1 more source