Results 61 to 70 of about 1,129,729 (359)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Effects of dietary brown propolis on nutrient intake and digestibility in feedlot lambs

open access: yesRevista Brasileira de Zootecnia, 2014
The present study tested brown propolis in crude or extract form as a feed supplement for feedlot lambs to identify the type that most improves in vivo nutrient digestibility. Digestibility was assessed by both total fecal collection and internal markers
Jonilson Araújo da Silva   +6 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Influence of protected organic acid blends and diets with different nutrient densities on growth performance, nutrient digestibility and faecal noxious gas emission in growing pigs

open access: yesVeterinární Medicína, 2014
This study was conducted to evaluate the effects of dietary supplementation of protected organic acid blends including medium chain fatty acids and different nutrient density diets on growth performance, nutrient digestibility and faecal noxious gas ...
S.D. Upadhaya, K.Y. Lee, I.H. Kim
doaj   +1 more source

Nitrogen and energy partitioning in two genetic groups of pigs fed low-protein diets at 130 kg body weight [PDF]

open access: yes, 2015
The aim was to evaluate the effect of low-protein (LP) or low-amino acid diets on digestibility, energy and nitrogen (N) utilisation in 2 genetic groups (GG) of pigs (129±11 kg BW). Duroc×Large White (A) pigs were chosen to represent a traditional GG for
Colombini, Stefania   +7 more
core   +3 more sources

Predicting nutrient digestibility and energy value for broilers.

open access: yesPoultry Science, 2019
Digestibility coefficients of nutrients, metabolizable energy (ME), net energy (NE) and the ratio of NE to ME (NE/ME) of 20 diets were measured in broiler chickens (1 to 21 d).
S. Cerrate   +3 more
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

A taste for growth: Rapeseed lecithin improves the feed intake of post‐juvenile rainbow trout (Oncorhynchus mykiss)

open access: yesJournal of the World Aquaculture Society
Feed formulations low in fish meal and fish oil can decrease feed intake and nutrient digestibility. Dietary application of lecithins could improve growth performance and nutrient digestibility; however, knowledge about specific lecithins and their ...
Frederik Kaiser   +3 more
doaj   +1 more source

Dietary Ground Flaxseed Increases Serum Alpha-Linolenic Acid Concentrations in Adult Cats

open access: yesAnimals, 2022
We evaluated effects of dietary ground flaxseed on fecal and serum alpha-linolenic acid (ALA) concentrations, nutrient digestibility, and stool quality in female and male adult cats (n = 20 (8 males, 12 females); 3.95 ± 1.49 years of age (mean ± SD); 3 ...
Matthew R. Panasevich   +3 more
doaj   +1 more source

Quantification of nutrient supply in forage-based diets for beef cattle [PDF]

open access: yes, 2009
End of Project ReportIntroduction Cattle rearing systems in Ireland are predominantly grass-based as 80% of agricultural land is dedicated to grassland (silage, hay and pasture) (CSO, 2007).
McGee, Mark   +2 more
core  

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