Results 61 to 70 of about 183,174 (259)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

The geographic patterns of macro- and micronutrient consumption in China: a comparison between urban and rural populations

Cogent Food & Agriculture
The Chinese dietary structure has experienced remarkable shifts over the last decade, yet a comprehensive and spatially granular assessment of essential nutrient intake remains limited.
Yang Luo, Jing Chen, Wei Ning Xiu, Tao Liang, Yan Wang, Qian Xue   +5 more
doaj   +1 more source

Nutrient requirements and optimisation fo intakes [PDF]

British Medical Bulletin, 2000
In 1991, dietary reference values were published in the UK. These refer to nutrients and provide the basis for dietary advice. To complement this, practical food-based guidance on how to plan a healthy and balanced diet has been developed. Interest continues in how best to establish guidance which helps individuals modify their diets so as to better ...
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Nutrient Intake Adequacy among Adults in Indonesia and Malaysia: A Systematic Review and Meta-Analysis

Current Developments in Nutrition
Under- or overconsumption of nutrients significantly increases the likelihood of future health impairments. However, comprehensive studies that systematically analyzed nutrient intake, especially among adults, are limited. This systematic review and meta-
Rina Agustina, Rachmi Mufida, Wanda Lasepa, Ajeng Mustika, Ardini Debilauralita, Sepriani T Limbong, Deviana AS Siregar, Erfi Prafiantini, Nurul RM Manikam, Pradana Soewondo   +9 more
doaj   +1 more source

Asupan zat gizi, status gizi dan motivasi serta hubungannya dengan produktivitas pekerja perempuan pada bagian pencetakan di Pabrik Bakpia Pathuk 25 Yogyakarta

Jurnal Gizi Klinik Indonesia, 2010
Background: Employees’ productivity is closely related with nutritional condition. Nutritional condition can be physically assessed by determining nutrition status. One’s nutrition status is directly influenced by nutrient intake.
Rina Kusriyana, Siti Helmyati, R Dwi Budiningsari   +2 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Assessment of energy and nutrient intake adequacy and dietary diversity of pregnant women in Abidjan

NAJFNR
Background: Dietary diversity is a potential indicator of adequate nutrient intake. Aims: The study assessed dietary diversity and adequacy of nutrient intake among pregnant women in Abidjan (Côte d’Ivoire).
Stephane Claver Vanie, Kouakou Nestor Kouassi, Patrick Aubin Dakia, Grodji Albarin Gbogouri   +3 more
doaj   +1 more source