Results 51 to 60 of about 260,033 (302)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Проблемы особо опасных инфекций, 2009 5 experimental nutritious bases were prepared out of plant materials (soybeans, soymilk, sugar-beet molasses - sugar syrup), and their physical and chemical parameters and amino-acid composition were studied.
A. A. Kurilova +3 more
doaj +1 more source
Video_2_Cellular memory of rapid growth is sensitive to nutrient depletion during starvation.AVI
, 2022 Bacteria frequently encounter nutrient fluctuations in natural environments, yet we understand little about their ability to maintain physiological memory of previous food sources.
Spencer Cesar (14145123) +2 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Проблемы особо опасных инфекций, 2018 Objective of the study was to develop a solid medium on the basis of enzyme digest of corn-steep extract for manufacturing of live plague vaccine and storage of plague agent strains. Materials and methods.
S. E. Gostishcheva +8 more
doaj +1 more source
Abiotic and biotic factors in the nutrient solution and filter skin (Schmutzdecke) of slow filters integrated to closed hydroponic greenhouse systems [PDF]
, 2006 Rapid pathogen dispersal by circulating nutrient solutions in closed hydroponic systems poses a major threat to this production method. Slow filtration is very effective against important fungal pathogens such as Phytophthora cryptogea and Pythium ...
Furtner, Bernhard
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Проблемы особо опасных инфекций, 2018 Objective of the study was to test the nutrient medium based on the enzymatic hydrolysate of corn extract condensed for a scaled production of live plague vaccine and to check the quality of the obtained batches against the specified parameters ...
S. E. Gostishcheva +5 more
doaj +1 more source
Towards Design For a Nutrient Trading Programme to Improve Water Quality in Lake Rotorua [PDF]
This paper explores how to enhance the role for academic research (natural sciences, economics and their integration; and stakeholder management) within the development and implementation of water quality policy in New Zealand. Our focus is on the use of
Kerr, Suzi, Fairman, David, Lauder, Glen
core +1 more source