Results 51 to 60 of about 1,476,093 (293)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Reference Values of Grain Nutrient Content and Removal for Corn

Revista Brasileira de Ciência do Solo, 2019
: Unchanged reference values of grain nutrient contents for corn have been used for over 20 years, despite yield increases, the development of new hybrids, and modifications to cropping systems, especially the establishment of in-season second crops and ...
Aildson Pereira Duarte, Mônica Ferreira de Abreu, Eros Artur Bohac Francisco, Douglas de Castilho Gitti, Gabriel Barth, Claudinei Kappes   +5 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Treatment of Liquid Digestate by Green Algal Isolates from Artificial Eutrophic Pond

Molecules, 2022
The ability of aquatic microalgae to treat the liquid digestate obtained from the anaerobic digestion of plant waste was investigated. Microalgae were isolated from natural environment for a laboratory-scale cultivation and were then used to remove ...
Ewelina Sobolewska, Sebastian Borowski, Paulina Nowicka-Krawczyk, Katarzyna Banach   +3 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

COD and nutrient removal from urban effluent by desmodesmus subspicatus

Semina: Ciências Exatas e Tecnológicas, 2019
The aim of this research was to evaluate the heterotrophic growth and removal of COD and nutrients (nitrogen and phosphorus) of green microalgae Desmodesmus subspicatus from domestic wastewater collected in pilot plant of treatment and water reuse of the
Reinaldo Gaspar Bastos, Vanessa Ribeiro Urbano, Fabiane Karen Godoy, Luiz Felipe Arjonilla de Mattos, Claudinei Fonseca Souza   +4 more
doaj   +1 more source

Water Treatment Effect, Microbial Community Structure, and Metabolic Characteristics in a Field-Scale Aquaculture Wastewater Treatment System

Frontiers in Microbiology, 2020
Avoiding and mitigating the introduction of harmful effluent into the environment must be a key part of intensive industrial aquaculture development in order to minimize pollution impacts.
Zhifei Li, Zhifei Li, Ermeng Yu, Ermeng Yu, Kai Zhang, Kai Zhang, Wangbao Gong, Wangbao Gong, Yun Xia, Yun Xia, Jingjing Tian, Jingjing Tian, Guangjun Wang, Guangjun Wang, Jun Xie, Jun Xie   +15 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source