Results 91 to 100 of about 691,761 (301)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Solution for Soilless Culture Nutrient

, 2023
The use case aims to semantically represent heterogeneous IoT devices using unified IIoT ontology, based on well-established ontologies, in order to mitigate interoperability problems in industrial applications (data interoperability and interconnectivity).
openaire   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Nitrogen and potassium supply and the morphogenic and productive characteristics of marandu palisadegrass Suprimento combinado de nitrogênio com potássio para o capim-marandu: características morfogênicas e produtivas

Revista Brasileira de Zootecnia, 2010
The objective of this work was to study morphogenic characteristics, and dry matter production of roots and shoots of marandu palisadegrass (Brachiaria brizantha cv.
Marcio Mahmoud Megda, Francisco Antonio Monteiro   +1 more
doaj   +1 more source

Measurement of transpiration in Pinus taeda L. and Liquidambar styraciflua L. in an environmental chamber using tritiated water [PDF]

Transpiration rates of loblolly pine (Pinus taeda L.) and sweetgum (Liquidambar styraciflua L.) were measured at two different atmospheric water vapor pressure deficits (V.P.D.) in a controlled environment growth chamber using tritiated water as a tracer.
Czoch, J. K., Levy, G. F., Sonenshine, D. E.   +2 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Cultivo sem solo do morangueiro com três métodos de fertirrigação Three fertigation methods in soilless production of the strawberry crop

Ciência Rural, 2009
O objetivo deste trabalho foi avaliar o crescimento e a produtividade de frutas de dois clones de morangueiro em sistema fechado sem solo e com três métodos de fertirrigação.
Jerônimo Luiz Andriolo, Djeimi Isabel Jänisch, Clarisse Silva Oliveira, Carine Cocco, Odair José Schmitt, Francieli Lima Cardoso   +5 more
doaj  

Application of Deep Sea Water (DSW) for Nutrient Supplement in Hydroponics Cultivation of Tomato : Effect of Supplemented DSW at Different EC Levels on Fruit Properties [PDF]

, 2007
Deep sea water (DSW) has the potential characteristics for nutrient supplement in hydroponics cultivation. This experiment was carried out to evaluate the application of DSW as a nutrient supplement for tomato cultivation in hydroponics system.
Chadirin, Y. (Yudi), Matsuoka, T. (Takahisa), Suhardiyanto, H. (Herry), Susila, A. D. (Anas)   +3 more
core