Results 61 to 70 of about 4,136,671 (300)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

PRODUÇÃO DE ALFACE HIDROPÔNICA UTILIZANDO BIOFERTILIZANTE COMO SOLUÇÃO NUTRITIVA

open access: yesRevista Caatinga, 2009
To evaluate the utilization of the biofetilizer substituting nutrient solution in hydroponic lettuce was carried out the study in greenhouse at Environmental Science Departament of the UFERSA, located in Mossoró, Rio Grande do Norte State, Brazil.
NILDO DA SILVA DIAS   +4 more
doaj  

Modern plant cultivation technologies in agriculture under controlled environment: a review on aeroponics

open access: yesJournal of Plant Interactions, 2018
This review paper describes a novel approach to plant cultivation under soil-less culture. At present, global climate change is expected to raise the risk of frequent drought.
Imran Ali Lakhiar   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An 15N study of the effects of nitrate, ammonium, and nitrate + ammonium nutrition on nitrogen assimilation in Zea Mays L. [PDF]

open access: yes, 1984
Bibliography: leaves 113-134.A brief review of the literature on the effects of nitrate and ammonium nitrogen sources on plant growth, and the assimilation of those nitrogen sources, has been presented.
Murphy, Andrew Telfer
core   +1 more source

Avaliação do desempenho de um sistema automático para controle da fertirrigação do tomateiro cultivado em substrato Performance evaluation of an automatic system for tomato fertigation control in substrate

open access: yesEngenharia Agrícola, 2009
Este trabalho teve por objetivo avaliar o desempenho de um sistema de controle automático de fertirrigação para a produção do tomateiro em substrato de areia, comparativamente ao sistema de controle convencional quanto à redução de solução nutritiva.
Antonio J. Steidle Neto   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

USDA Table of Nutrient Retention Factors, Release 6 (2007)

open access: yes, 2017
Release 6, of this data set, replaces the previous release, Release 5, issued in 2003. The data set contains the factors for calculating retention of 26 vitamins, minerals and alcohol during food preparation.
Nutrient Data Lab (17478261)
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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