Results 111 to 120 of about 153,995 (308)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Priority effects outweigh nitrogen deposition in shaping C3–C4 grass competition in desert steppe ecosystems

Global Ecology and Conservation
Nitrogen (N) deposition and altered sowing patterns are key drivers of grassland community dynamics, influencing species interactions, resource allocation, and ecosystem functioning.
Kun Zhao, Fen Wang, Qian Liu, Haina Hu, Shenyi Jiang, Hui Gao, Chunxue Han, Mengli Zhao, Guodong Han, Haigang Li   +9 more
doaj   +1 more source

Ideotyping integrated aquaculture systems to balance soil nutrients.

, 2011
Due to growing land scarcity and lack of nutrient inputs, African farmers switched from shifting cultivation to continuous cropping and extended crop area by bringing fragile lands such as river banks and hill slopes into production.
Muendo, P.N., Verreth, J.A.J., Mora Vallejo, A.P., Stoorvogel, J.J., Verdegem, M.C.J.   +4 more
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Comparing feed intake, utilization of protein and energy for growth and body composition in S. solea fed natural and commercial diets

, 2009
The present work was carried out to study the effect of polychaete Nereis virens on feed intake, utilization of protein and energy for growth and body composition in sole (S. solea). It is hypothesized that intake, efficiencies of protein utilization and
Kroeckel, S., Verreth, J.A.J., Ende, S.S.W., Schrama, J.W., Schneider, O.   +4 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Combined Application of Chemical and Organic Fertilizers: Effects on Yield and Soil Nutrients in Spring Wheat under Drip Irrigation

Agronomy
In this study, we established a feasible fertilization programming method for wheat production by exploring the effects of the combined application of chemical and organic fertilizers on wheat yield, nutrient uptake, soil nutrient content, and fertilizer
Xiangjie Chang, Hao He, Liyang Cheng, Xiaojuan Yang, Shuai Li, Mengmeng Yu, Jifeng Zhang, Junhua Li   +7 more
doaj   +1 more source

Precision Feeding in Dairy Ration Cost Minimization Under Producer's Risk Management

The biophysical simulation data from Cornell Net Carbohydrate and Protein System were used in non-linear programming model for least cost ration incorporating ingredient nutrient and price variations.
Dillon, Carl R., Salim, Juma K.
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source