Results 41 to 50 of about 76,238 (313)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Quality of surface water related to land use: a case study in a catchment with small farms and intensive vegetable crop production in southern Brazil

Revista Brasileira de Ciência do Solo, 2014
Water degradation is strongly related to agricultural activity. The aim of this study was to evaluate the influence of land use and some environmental components on surface water quality in the Campestre catchment, located in Colombo, state of Parana ...
Karina Hacke Ribeiro, Nerilde Favaretto, Jeferson Dieckow, Luiz Cláudio de Paula Souza, Jean Paolo Gomes Minella, Luciano de Almeida, Michele Ribeiro Ramos   +6 more
doaj   +1 more source

Nutrients and Muscle Disease [PDF]

BioMed Research International, 2015
Myopathies, classified as either hereditary or acquired, lead to common, clinically relevant complaints including fatigue, progressive strength loss, myalgias, and cramps. Important progress has been made in the comprehension of the molecular mechanisms underlying muscle diseases but, in the majority of cases, their clinical management is symptom ...
E. Nisoli, R. Grange, G. D'Antona
openaire   +3 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Dinámica y Determinación de Nutrientes y Productividad de la Cuenca del Río Guayas. [PDF]

, 2017
La Facultad de Ingenieria Marítima, Ciencias Biológicas, Oceanográficas y Recursos Naturales (FIMCBOR) de la Escuela Superior Politécnica del Litoral ESPOL, es una unidad académica en donde se desarrollan múltiples proyectos de investigación con sus ...
Bayona, Julio, Basurto, Stefanie
core  

Caracterización y evaluación nutricional de las dietas macrobióticas Ma-Pi Characterization and nutritional evaluation of the Ma-Pi macrobiotic diets

Revista Cubana de Investigaciones Biomédicas, 2008
Existe desconocimiento y confusión general sobre la alimentación macrobiótica. En el Instituto Finlay se están realizando, desde hace siete años, diferentes ensayos clínicos con las dietas macrobióticas Ma-Pi, desarrolladas por Mario Pianesi, fundador y ...
Carmen Porrata Maury, Manuel Hernández Triana, Alfredo Abuín Landín, Concepción Campa Huergo, Mario Pianesi   +4 more
doaj  

Nutrient Adequacy

, 2014
Key Messages "Nutrient adequacy, a result of consumption of sufficient amounts of all essential nutrients and energy to meet individual requirements, is a prerequisite for normal growth, development and health. " Two thirds or more of hospital patients suffer from malnutrition at initial presentation.
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Resposta da macieira e fluxo de nitrogênio em um solo submetido à aplicação de fontes de nutrientes e manejo de plantas de cobertura [PDF]

, 2012
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Curso de Agronomia.O estado de Santa Catarina (SC) possui a maior área cultivada com a macieira do Brasil. Em geral, a macieira é cultivada em solos com médios a altos
OLIVEIRA, BRUNO SALVADOR
core  

Determinación proximal de los principales componentes nutricionales de seis variedades de leguminosas: arveja, garbanzo, haba, lenteja, maní y soya [PDF]

, 2012
El objetivo principal de este trabajo fue la determinación proximal de los principales nutrientes de las siguientes variedades de leguminosas de grano seco: arveja, garbanzo, lenteja, haba, maní y soya.
Polo Chávez, Iván Andrés
core   +2 more sources