Results 111 to 120 of about 1,576,936 (310)
Frontiers in PharmacologyBackgroundMacrophage polarization plays a pivotal role in shaping the tumor microenvironment and influencing cancer progression. Long non-coding RNAs (lncRNAs) have emerged as important regulators of this process.
Yihan Liu +5 more
doaj +1 more source
Integrated nutrient management, soil fertility, and sustainable agriculture: current issues and future challenges [PDF]
The challenge for agriculture over the coming decades will be to meet the world's increasing demand for food in a sustainable way. Declining soil fertility and mismanagement of plant nutrients have made this task more difficult.
Goletti, Francesco +2 more
core
Scaling and optimal synergy: Two principles determining microbial growth in complex media
, 2015 High-throughput experimental techniques and bioinformatics tools make it possible to obtain reconstructions of the metabolism of microbial species. Combined with mathematical frameworks such as flux balance analysis, which assumes that nutrients are used
Amaral, Luís A. Nunes +3 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Neural electrodes for brain‐computer interface system: From rigid to soft
BMEMatBrain‐computer interface (BCI) is an advanced technology that establishes a direct connection between the brain and external devices, enabling high‐speed and real‐time information exchange. In BCI systems, electrodes are key interface devices responsible
Dan Yang +7 more
doaj +1 more source
Nutrient Addition Effects on Phytoplankton Communities in the Amazon River Plume [PDF]
The types and abundance of phytoplankton is largely controlled by availability of sunlight and bioavailable nutrients. Phytoplankton require essential nutrients including nitrate, phosphate, and silicate to grow, so understanding the role of these ...
Klotz, Vivian +5 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Watershed Investigative Support to the Poteau Valley Improvement Authority: Stream Water Quality to Support HUC 12 Prioritization in the Lake Wister Watershed, Oklahoma [PDF]
, 2018 Nonpoint source pollution associated with human land use (agriculture and urbanization) is one of the leading causes of impairment to waterways in the United States (EPA, 2000).
Austin, Bradley J. +2 more
core +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The relationship between aquatic macrophytes and water quality in Nta-Wogba Stream, Port Harcourt, Nigeria [PDF]
, 2011 An empirical survey of macrophytes distribution and biomass from four stations, along Nta-wogba stream in Port Harcourt, Nigeria, was conducted between April and December 2007, to quantify the relationship between biomass, in stream nutrients and ...
Akinrotimi, O.A. +2 more
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