Results 151 to 160 of about 2,370,327 (359)

Tools for managing manure nutrients [PDF]

, 2002
Manures are a valuable source of nutrients (and organic matter), and can be seen as a method of transferring nutrients around the farm (for homeproduced manures) or as a method of importing fertility (imported manures or composts). Good manure management
Philipps, Lois, Shepherd, Mark, Webb, John   +2 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Discovery of Jaspamycin from marine-derived natural product based on MTA3 to inhibit hepatocellular carcinoma progression

Scientific Reports
Studies have underscored the pivotal role of metastasis-associated protein 3 (MTA3) as a cancer regulator, yet its potential as a drug target across cancers necessitates comprehensive evaluation.
Yihan Liu, Tong Lu, Runze Li, Rui Xu, Denis Baranenko, Lida Yang, Dan Xiao   +6 more
doaj   +1 more source

Green manure crops for low fertility soils [PDF]

, 2019
Organic crop production is growing, but crop yields are still below potential. The purpose of our project “Nutrients for higher organic yields (NutHY)” is to increase yields and resource efficiency in organic crop production by optimizing nutrient supply.
Hansen, Veronika, Magid, Jakob, Müller-Stöver, Dorette   +2 more
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Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Porous starch as an effective carrier for sustained release and bioactivity protection of cannabidiol full spectrum oil

Current Research in Food Science
Full-spectrum cannabidiol oil (CFSO) has attracted growing attention across industries for its multiple health benefits, but its poor water solubility and low bioavailability remain unresolved challenges.
Jiangfei Li, Naicheng Xin, Guanjun Ye, Zhilong Zhou, Junwen Wang, Ting Ju, Heqi Gao, Yang Gao, Xianghui Meng, Alejandro Cifuentes, Weihong Lu, Yingchun Zhang   +11 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Thiamine, gastrointestinal beriberi and acetylcholine signaling

Frontiers in Nutrition
Research has highlighted numerous detrimental consequences of thiamine deficiency on digestive function. These range from impaired gastric and intestinal motility to aberrant changes in pancreatic exocrine function, gastric acidity and disturbances in ...
Elliot Overton, Alina Emelyanova, Victoria I. Bunik, Victoria I. Bunik, Victoria I. Bunik   +4 more
doaj   +1 more source

Investigating the role that the Southern Ocean biological pump plays in determining global ocean oxygen concentrations and deoxygenation [PDF]

, 2013
Global ocean circulation connects marine biogeochemical cycles through the long-range transport of nutrients and oxygen with the Southern Ocean (SO) acting as a water mass crossroads. The biological pump in the SO has been shown to play an important role
Keller, David, Oschlies, Andreas
core