From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The importance of nutrition in the life cycle [PDF]
Nutrition plays a crucial role from the moment of conception to the final years of life, shaping our health outcomes and improving quality of life. The importance of nutrition in one’s life starts even before birth: during pregnancy, the nutritional ...
Agdeppa, Imelda Angeles
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Personalized Nutrition: How to make it possible? [PDF]
The advancing of economic and technology in the last 1–2 centuries that characterized by industrialization, urbanization, and globalization have changed human lifestyle worldwide.
Ardini, Witri, Bardosono, Saptawati
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Analysis of food sources and nutrient intakes of Filipino breastfeeding mothers in 2018 and 2019 Expanded National Nutrition Survey [PDF]
Objectives: This study evaluated the food and nutrient intake of Filipino breastfeeding mothers and identified the top food sources of nutrients in their diet.
Ducay, Apple Joy D. +3 more
core +1 more source
Scientific Opinion on the substantiation of a health claim related to <em>Saccharomyces cerevisiae</em> var. <em>boulardii</em> CNCM I-3799 and reducing gastro-intestinal discomfort pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]
<p>Following an application from Lesaffre International/Lesaffre Human Care, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies was ...
EFSA Panel on Dietetic Products, Nutrition and Allergies
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Scientific Opinion on the substantiation of a health claim related to <em>Rhodiola rosea</em> L. extract and reduction of mental fatigue pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]
<p>Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an ...
EFSA Panel on Dietetic Products, Nutrition and Allergies
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The role of nutrition and pancreatic enzyme replacement therapy in children with cystic fibrosis [PDF]
Background Cystic fibrosis (CF) is an inherited genetic disorder with high mortality and morbidity. CF is strongly correlated with malnutrition due to higher energy losses, pancreatic insufficiency, chronic inflammation, higher resting energy expenditure,
Cheng, William, Kadim, Muzal
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