FEBS Open Bio, EarlyView.Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source
Environmental Health and Preventive Medicine, 2019 Background Traditional toxicological studies focus on individual compounds. However, this single-compound approach neglects the fact that the mixture exposed to human may act additively or synergistically to induce greater toxicity than the single ...
Weifeng Mao +4 more
doaj +1 more source
Nutrition risk in age-related residential care : prevalence and associated factors in adults of advanced age : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition and Dietetics, Massey University, Albany, New Zealand [PDF]
, 2017 Background: The New Zealand population is rapidly ageing. Adults of advanced age (≥85 years) are one of the fastest growing population groups with numbers expected to double by 2036.
Senior, Stacey Marie
core
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Viruses, 2018 The accurate virus detection, strain discrimination, and source attribution of contaminated food items remains a persistent challenge because of the high mutation rates anticipated to occur in foodborne RNA viruses, such as hepatitis A virus (HAV).
Zhihui Yang +4 more
doaj +1 more source
Nutrition assessment and MASH severity in children using the Healthy Eating Index. [PDF]
Hepatol Commun, 2023 Jain AK +16 more
europepmc +1 more source
The link between poverty and malnutrition : a household theoretic approach [PDF]
Past studies have identified nutrition exclusively with nutrient intake. A better definition of nutrition would critically affect the link between poverty and malnutrition and would affect the implications for policies designed to improve the nutritional
Schiff, Maurice, Valdes, Alberto
core
Addressing nutritional literacy in preschool learning environments [PDF]
, 2017 INTRODUCTION: Obesity among preschool children is more common among lower-income families. Prevalence of type 2 diabetes in U.S. Mexican and African American populations has steadily increased and is associated with modifiable risk factors, such as poor ...
Warren, Cynthia
core +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Development and evaluation of the Food Bank Health and Nutrition Assessment. [PDF]
Public Health Nutr, 2023 Nguyen CJ +7 more
europepmc +1 more source