Results 61 to 70 of about 1,571,341 (314)

Nutrition and Metabolic Support in Burn

Türk Yoğun Bakim Derneği Dergisi, 2011
Burn injury results in a dramatic increase of the basal metabolic rate. Severe burn injury nearly doubles resting energy expenditure and hypermetabolism associated with burn results in a loss of body fat stores and a loss of visceral and structural ...
Perihan Ergin Özcan
doaj  

Research progress of prevention and nursing of pulmonary infection after tracheotomy in elderly patients with intracerebral hemorrhage (老年脑出血患者气管切开术后肺部感染预防护理研究进展)

中西医结合护理, 2023
The pulmonary infection after tracheotomy is associated with poor prognosis of elderly patients with intracerebral hemorrhage. This paper summarized the influencing factors and preventive nursing measures of pulmonary infection after tracheotomy, in ...
ZHAO Yangshuang (赵杨爽), DENG Ying (邓颖), HUANG Shan (黄山)   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effect of perioperative individualized nutrition intervention on pancreatic surgery outcomes: a prospective single-center study

Journal of Health, Population and Nutrition
Background There is currently a lack of reports on prospective randomized controlled trials (RCTs) focused on personalized nutritional support in pancreatic surgery.
Qing Chen, Chunhong Xiao, Xusangni Li, Qian Li, Huishuang Wu, Meiping Wang, Weixuan Hong, Aiwen Huang   +7 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Probiotics and gastrointestinal disorders: an umbrella meta-analysis of therapeutic efficacy

European Journal of Medical Research
Background Probiotic interventions are increasingly considered for alleviating gastrointestinal disorders such as diarrhea, nausea, bloating, and epigastric discomfort.
Qingfang Zeng, Pingdong Li, Huaiyang Wu, Yunying Zhuang, Yonggang Zhang, Sanaz Asemani, Parmida Jamilian, Mehrdad Jamali, Haixia Yu   +8 more
doaj   +1 more source

Long-term indwelling trans-anal ileus tube placement and nursing management for an elderly patient with intestinal obstruction (1例高龄肠梗阻患者长期留置经肛型肠梗阻导管的护理体会)

中西医结合护理
This article summarized the nursing practice of an elderly patient with acute exacerbation of chronic cholecystitis complicated by intestinal obstruction during long-term indwelling trans-anal ileus tube placement.
ZHANG Jia (张佳), SUN Xin (孙鑫)
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source