Results 61 to 70 of about 8,469,554 (311)

Perioperative nutritional support

Journal of British Surgery, 1993
The relationship between preoperative malnutrition and morbi-mortality has been documented for years. Despite the existence of tools that allow its detection, and therefore treat this entity, their introduction into clinical practice is not widespread.
B J, Moran, A A, Jackson
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Nutrition and Metabolic Support in Burn

Türk Yoğun Bakim Derneği Dergisi, 2011
Burn injury results in a dramatic increase of the basal metabolic rate. Severe burn injury nearly doubles resting energy expenditure and hypermetabolism associated with burn results in a loss of body fat stores and a loss of visceral and structural ...
Perihan Ergin Özcan
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Effect of perioperative individualized nutrition intervention on pancreatic surgery outcomes: a prospective single-center study

Journal of Health, Population and Nutrition
Background There is currently a lack of reports on prospective randomized controlled trials (RCTs) focused on personalized nutritional support in pancreatic surgery.
Qing Chen, Chunhong Xiao, Xusangni Li, Qian Li, Huishuang Wu, Meiping Wang, Weixuan Hong, Aiwen Huang   +7 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Case study: nutritional considerations in the head and neck cancer patient

The South African Journal of Clinical Nutrition, 2022
Head and neck squamous cell cancer (HNSCC) involves cancer of the oral cavity, oropharynx, hypopharynx and larynx. By virtue of the tumour location, nutrition support in this patient cohort can be extremely challenging.
Nathaniël Van Wyk
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Probiotics and gastrointestinal disorders: an umbrella meta-analysis of therapeutic efficacy

European Journal of Medical Research
Background Probiotic interventions are increasingly considered for alleviating gastrointestinal disorders such as diarrhea, nausea, bloating, and epigastric discomfort.
Qingfang Zeng, Pingdong Li, Huaiyang Wu, Yunying Zhuang, Yonggang Zhang, Sanaz Asemani, Parmida Jamilian, Mehrdad Jamali, Haixia Yu   +8 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source