Results 81 to 90 of about 8,469,554 (311)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Huli yanjiu, 2020 [Objective]To explore relationship between nutritional risk of patients with diabetic foot and their clinical prognosis and quality of life.[Methods]Totally 319 hospitalized patients with diabetic foot in department of endocrinology in Foshan traditional
HUANG Lirong +5 more
doaj
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
The Role of Microbiome and Metabolomics in Personalized ICU Nutrition
Personalized nutrition in the intensive care unit (ICU) has evolved from traditional caloric replacement strategies toward a multidimensional, biology-driven model that incorporates microbiome ecology and metabolomic signatures.
Santiago M. Herrero +1 more
core +1 more source
中西医结合护理This paper summarizes the application effect of Traditional Chinese Medicine gargle in 1 a severe stroke patient with catheterization. In addition to the conventional treatment of stroke, comprehensive nursing interventions such as monitoring state of ...
LI Jiaxing (李佳星) +4 more
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Breastfeeding Promotion Research: The ES/WIC Nutrition Education Initiative and Economic Considerations [PDF]
Educating low-income women about the advantages of breastfeeding their babies increases the number who breastfeed. This report summarizes the results of four projects that focused primarily on promoting breastfeeding, which is considered to be the most ...
Weimer, Jon P.
core
Complications and Prevention of the Parenteral Nutritional Support in the Intensive Care Unit [PDF]
, 2013 Nutritional support is one of the therapeutic modalities in the intensive care unit (ICU). Recently enteral feeding is recommended to start as soon as possible especially within 24 or 48 hours after admission.
장지영, 이재길, 이승환
core