Results 71 to 80 of about 1,571,341 (314)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Integrated Pharmacy Research and Practice, 2018 Maram Gamal KatoueDepartment of Pharmacology and Therapeutics, Faculty of Pharmacy, Kuwait University, Kuwait Background: Parenteral nutrition (PN) therapy is a complex and critical therapy that requires special clinical knowledge, skills, and practice ...
Katoue MG
doaj
An investigation of nutrition risk among hospitalised adults of advanced age admitted to the AT&R wards at North Shore and Waitakere Hospitals : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition and Dietetics at Massey University, Albany, New Zealand [PDF]
, 2015 Background: In line with the global trend of an ageing population, the number and proportion of New Zealanders aged 65 years and older is increasing.
Popman, Amy
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Huli yanjiu, 2020 [Objective]To explore relationship between nutritional risk of patients with diabetic foot and their clinical prognosis and quality of life.[Methods]Totally 319 hospitalized patients with diabetic foot in department of endocrinology in Foshan traditional
HUANG Lirong +5 more
doaj
The expected effects of the National School Nutrition Programme: Evidence from a case study in Cape Town, Western Cape [PDF]
, 2019 Magister Artium - MASchool feeding programmes have become a worldwide poverty reduction strategy that are designed to enhance human capital, i.e. nutrition and education.
Sanousi, Mohammed
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Nutritional Support in the ICU
BMJAbstract Critical illness is a complex condition that can have a devastating impact on health and quality of life. Nutritional support is a crucial component of critical care that aims to maintain or restore nutritional status and muscle function. A one-size-fits-all approach to the components of nutritional support has not proven beneficial.
Reignier, Jean +3 more
openaire +3 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source