Results 71 to 80 of about 1,561,525 (302)
中西医结合护理This article summarized the nursing practice of an elderly patient with acute exacerbation of chronic cholecystitis complicated by intestinal obstruction during long-term indwelling trans-anal ileus tube placement.
ZHANG Jia (张佳), SUN Xin (孙鑫)
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
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Exploiting biodiversity of traditional crops for mainstreaming nutrition sensitive agriculture in Nepal [PDF]
, 2020 Traditional crops cultivated and consumed over generationsare important components of agrobiodiversity and support dietary diversity, productivity and livelihoods of marginalized populations in Nepal. This paper outlines the value of traditional nutrient
Gauchan, D.
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Role of Nutrition in Alcoholic Liver Disease: Summary of the Symposium at the ESBRA 2017 Congress. [PDF]
, 2018 The symposium, "Role of Nutrition in Alcoholic Liver Disease", was held at the European Society for Biomedical Research on Alcoholism Congress on 9 October 2017 in Crete, Greece. The goal of the symposium was to highlight recent advances and developments
Feldstein, Ariel E +8 more
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FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
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Integrated Pharmacy Research and Practice, 2018 Maram Gamal KatoueDepartment of Pharmacology and Therapeutics, Faculty of Pharmacy, Kuwait University, Kuwait Background: Parenteral nutrition (PN) therapy is a complex and critical therapy that requires special clinical knowledge, skills, and practice ...
Katoue MG
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FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
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Huli yanjiu, 2020 [Objective]To explore relationship between nutritional risk of patients with diabetic foot and their clinical prognosis and quality of life.[Methods]Totally 319 hospitalized patients with diabetic foot in department of endocrinology in Foshan traditional
HUANG Lirong +5 more
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FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
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