Results 71 to 80 of about 6,845,687 (356)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Physical exercise in type 1 diabetes: recommendations and care
Motriz: Revista de Educacao FisicaThe management of type 1 diabetes mellitus (T1DM) is based on three pillars: insulin therapy, nutrition, and regular practice of physical activity. Physical exercises are associated with metabolic demands that depend on the individual's energy stores and
Luis Paulo Gomes Mascarenhas +5 more
doaj +1 more source
Nutritional issues in patients with cancer [PDF]
Intestinal Research, 2019 Cancer is a catabolic inflammatory disease that causes patients to often experience weight loss, or even cachexia in severe cases. Undernourishment in patients with cancer impairs the quality of life and therapeutic response, further leading to poor ...
Duk Hwan Kim
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Clinical Interventions in Aging, 2023 Chad Yixian Han,1 Yogesh Sharma,2,3 Alison Yaxley,1 Claire Baldwin,1 Richard Woodman,2 Michelle Miller1 1Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Adelaide, SA, Australia; 2College of Medicine and Public ...
Han CY +5 more
doaj
Clinically Practical and Affordable Lifestyle Modification to Prevent Diabetes Mellitus in Real Practice [PDF]
Diabetes & Metabolism JournalAs the prevalence of type 2 diabetes mellitus continues to rise, the development of effective and sustainable prevention strategies has become a critical public health priority.
Inji Lee +4 more
doaj +1 more source
Serum vitamin D decreases during chemotherapy: an Australian prospective cohort study [PDF]
, 2018 Background and Objectives: Vitamin D plays an important role in bone and muscle function, and cell prolifera-tion. The impact of chemotherapy and associated behavioural changes such as fatigue and sun avoidance on vit-amin D (25(OH) D) is unknown.
Isenring, Elisabeth +9 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
How to Feed Critically Ill Patients [PDF]
Journal of Acute Care Surgery, 2015 Nutrition therapy is challenging in critically ill patients. Critical illness is associated with catabolic stress, in which stress hormones and inflammatory mediators are activated, resulting in proteolysis.
Suk-Kyung Hong
doaj +1 more source
Chemotherapy-induced nausea and vomiting: A narrative review to inform dietetics practice [PDF]
, 2016 Chemotherapy-induced nausea and vomiting (CINV) are common nutrition-impact symptoms experienced by cancer patients. They exert a detrimental effect on dietary intake, risk of malnutrition and quality of life.
Isenring, Liz +4 more
core +3 more sources