Results 211 to 220 of about 5,371,978 (344)

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

Advanced Science, EarlyView.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao, Xiaofan Jiang, Md Moniruzzaman, Alexandra Mueller, Taskeen Iqbal Janjua, Nisha Tyagi, Zhi Qu, Kuan Yau Wong, Yuran Feng, Aayushi Ghodasara, Ekaterina Strounina, Benjamin P. Ross, Tushar Kumeria, Sumaira Z. Hasnain, Amirali Popat   +14 more
wiley   +1 more source

A study on the nutritional composition and shelf-life of Hanwoo cattle bone items during retail display. [PDF]

Food Sci Anim Resour
Hoa VB, Park WS, Yoo JY, Kandasamy S, Kang HB, Ham JS, Bae IS.   +6 more
europepmc   +1 more source

Advancing Precision Nutrition Through Multimodal Data and Artificial Intelligence

Advanced Science, EarlyView.
Individual responses to food vary dramatically, challenging traditional dietary advice. This review explores how the unique genetic makeup, gut microbiome, and brain activity shape host metabolic health. We examine how artificial intelligence integrates these multimodal data to predict individualized dietary needs, moving beyond one‐size‐fits‐all ...
Yuanqing Fu, Ke Zhang, Zelei Miao, Gaoyi Yang, Yujing Huang, Ju‐Sheng Zheng   +5 more
wiley   +1 more source

The Sir David Cuthbertson Medal Lecture 1991:The mechanisms and treatment of weight loss in cancer [PDF]

, 1992
Ball, Beck, Brennan, Burkinshaw, Chlebowski, Conyers, Cooper, Costa, Dinarello, Emery, Fearon, Fearon, Fearon, Fearon, Gear, Heber, Kenneth C. H. Fearon, Lampidis, Langstein, McIntosh, Nakashima, Nixon, Pain, Preston, te Velde, Tisdale, Warburg, Williams   +27 more
core   +1 more source

Approaching Scarless Wound Healing: From Passive Anti‐Fibrotic to Proactive and Programmable Pro‐Regenerative Strategies

Advanced Science, EarlyView.
This review outlines the wound healing process and factors influencing scar formation, explores how certain animals and human fetuses achieve scarless skin or tissue regeneration, and details tissue engineering material strategies employed in scarless wound dressings.
Meimei Fu, Zhuoyi Huang, Jintao Li, Yue Li, Zhou Fang, Yiwen Jiang, Keke Wu, Jinshan Guo   +7 more
wiley   +1 more source

Fruit Nutritional Composition and Seed Reserve Mobilization as Tools for Phenotypic Selection in Eugenia patrisii (Myrtaceae). [PDF]

Foods
Santos PPD, Gonçalves EV, de Carvalho JC, Costa KCPD, Pacheco AA, Viana CDS, Aguiar JPL, Fernandes AV, Martins AO, Araújo WL, Gonçalves JFC.   +10 more
europepmc   +1 more source

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

Advanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

Ecological and genetic regulation of nutritional composition, pasting properties and metabolomic profiles in foxtail millet. [PDF]

Food Chem X
Zhao X, Wang Y, Deng Z, Li Z, Yue M, Li H, Han Y.   +6 more
europepmc   +1 more source

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

Advanced Science, EarlyView.
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner, Truls Raastad, Max Ullrich, Stian F. Christiansen, Hazel Sutherland, James Boot, Eva Wozniak, Charles Mein, Emilie Dalbram, Jonas T. Treebak, Daniel J. Owens, David C. Hughes, Sue C. Bodine, Jonathan C. Jarvis, Adam P. Sharples   +14 more
wiley   +1 more source

Updating [Nutritional composition dataset of approved infant formula powder in China (2017-2024)] with [Nutritional composition dataset of approved older infant formula powder in China (2017-2024)]. [PDF]

Data Brief
Cai J, Li S, Wei Q, Wang H, Jiang Y, Jiao J.   +5 more
europepmc   +1 more source