Results 191 to 200 of about 10,826,082 (381)
This study investigates the expression and functional role of the deubiquitinase PSMD14 in PC, with a focus on the mechanism by which it promotes lactate accumulation–induced histone lactylation, thereby driving aberrant lipid metabolism. These findings establish that dual targeting of PSMD14 and the glycolysis–lactylation signaling axis may represent ...
Ri‐Shang Lu+10 more
wiley +1 more source
Observations on Some Metabolic and Nutritional Diseases Encountered Among Livestock in Egypt [PDF]
openalex +1 more source
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo+17 more
wiley +1 more source
Recent research has shown that biodegradable metals based on zinc (Zn) may be used as guided bone regeneration (GBR) membrane materials. This study examines their viability from the standpoints of material science and biology, reports on the state of research on Zn‐based GBR membranes, and suggests specific development plans based on the potential and ...
Kai Chen+12 more
wiley +1 more source
GEORGE BUDD (1808–1882) AND NUTRITIONAL DEFICIENCY DISEASES [PDF]
R. E. Hughes
openalex +1 more source
FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang+15 more
wiley +1 more source
Protein Reserves: Evidence for Their Utilization under Nutritional and Disease Stress Conditions
Hans Fisher+3 more
openalex +1 more source
Design and Evaluation by Nitrogen Balance and Blood Aminograms of an Amino Acid Mixture for Total Parenteral Nutrition of Adults with Gastrointestinal Disease [PDF]
G. Harvey Anderson+2 more
openalex +1 more source
This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun+15 more
wiley +1 more source