Results 91 to 100 of about 155,908 (273)

An Engineered Solidified Peptide Hemocyte Sponge as Nanomotor Storage to Combat Bacterial Colitis

open access: yesAdvanced Science, EarlyView.
Peptides immobilized via nickel coordination can stabilize the framework structure. Following coating with red blood cell membranes, these constructs are capable of continuously sequestering endotoxins and mitigating colonic pathogenic damage by alleviating bacterial‐induced ferroptosis.
Yuxin Fang   +8 more
wiley   +1 more source

Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat

open access: yesAdvanced Science, EarlyView.
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. ‌Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang   +22 more
wiley   +1 more source

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

open access: yesAdvanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao   +12 more
wiley   +1 more source

A Brief History of Bacterial Growth Physiology

open access: yesFrontiers in Microbiology, 2015
Arguably, microbial physiology started when Leeuwenhoek became fascinated by observing a Vorticella beating its cilia, my point being that almost any observation of microbes has a physiological component.
Moselio eSchaechter
doaj   +1 more source

Influence of Region, Harvest Year, and Variety on Stable Isotope Characterization of Xinjiang Rice From China

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Xinjiang rice isotopic differences were influenced by region, harvest year, variety, with southern rice had more positive δ13C, δ2H and δ18O values than northern. This study provides the first Xinjiang rice traceability data, aiding China's national rice database.
Menglin Zhang   +8 more
wiley   +1 more source

The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile

open access: yesNutrition Journal, 2008
This review will discuss some issues related to the risk/benefit profile of the use of dietary antioxidants. Thus, recent progress regarding the potential benefit of dietary antioxidants in the treatment of chronic diseases with a special focus on immune
Di Benedetto Giulia   +8 more
doaj   +1 more source

Risk Factors for Body Weight Loss After Gastrectomy for Gastric Cancer Analyzed From the JCOG1001 Phase III Trial

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To investigate the factors associated with BWL after gastrectomy using data from the phase III trial (JCOG1001). Methods This post hoc analysis included 728 patients from the JCOG1001. The percentage of BWL (%BWL) was defined as the proportion of decrease in body weight immediately before adjuvant chemotherapy initiation compared with that
Takanobu Yamada   +16 more
wiley   +1 more source

The application of methods of ecosystem analysis to the evaluation of water quality [PDF]

open access: yes, 1980
Guided by experience and the theoretical development of hydrobiology, it can be considered that the main aim of water quality control should be the establishment of the rates of the self-purification process of water bodies which are capable of ...
Kozhova, O.M.
core  

Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition [PDF]

open access: yes, 2015
Although the prevalence of malnutrition in the old age is increasing worldwide a synthetic understanding of the impact of aging on the intake, digestion, and absorption of nutrients is still lacking.
Bordoni, Alessandra   +11 more
core   +4 more sources

Bio‐Inspired Pancreas With Microfluidic Multi‐Component Hydrogel Microfibers for Exploring Pancreatic Exocrine and Endocrine Interactions

open access: yesAggregate, EarlyView.
A bionic pancreas model incorporating core‐shell microfibers that encapsulate pancreatic stellate cells (PSCs) and β‐cells provides valuable insights into PSCs activation, cell‐cell interactions, and diabetes progression. Furthermore, the potential of this bio‐inspired pancreas for drug screening is demonstrated by testing with a glucagon‐like peptide ...
Zhikun Huan   +4 more
wiley   +1 more source

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