Results 121 to 130 of about 99,865 (235)

Management of paediatric ulcerative colitis, part 1: Ambulatory care—An updated evidence‐based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine   +24 more
wiley   +1 more source

Impact of placental and peripheral blood DNA methylation on celiac disease susceptibility

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Several studies suggest that the first immunogenic insult in celiac disease (CeD) could occur during fetal development. The placenta is a key organ that could link the environment with the genome and future outcomes, including CeD.
Alba Hernangomez‐Laderas   +11 more
wiley   +1 more source

Late Quaternary population expansion in gray brocket deer [Subulo gouazoubira (G. Fisher, 1814), Cervidae, Mammalia] in Brazil

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT There is little information about the changes in the abundance of mammalian species in South America during the late Quaternary, which is a key parameter to understanding past ecological and evolutionary dynamics. Here, we describe a conspicuous increase in the abundance of the gray brocket deer (Subulo gouazoubira G.
Alex Hubbe   +21 more
wiley   +1 more source

How marine heatwaves are reshaping phytoplankton in the Northeast Pacific

open access: yesLimnology and Oceanography, EarlyView.
Abstract In 2015 and 2019, the Northeast Pacific has undergone significant heatwave events that strongly disrupted marine ecosystems functioning and services. Here we use the data collected by the Continuous Plankton Recorder (CPR) survey to investigate the changes in summer phytoplankton abundance and morphology and show an increase in prolate (i.e ...
Loïck Kléparski   +6 more
wiley   +1 more source

Heterotrophic dependence and bidirectional metabolite exchange dynamics in a temperate coral

open access: yesLimnology and Oceanography, EarlyView.
Abstract In temperate ecosystems, where cold, turbid waters constrain symbiotic potential, corals have evolved facultative symbiosis, providing an opportunity to explore coral energetics in the face of global climate change. We conducted an in situ light exclusion experiment on the facultatively symbiotic temperate coral Astrangia poculata to explore ...
Taylor R. Lindsay   +3 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

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