Results 161 to 170 of about 2,914,828 (294)

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Economics of altering the amount of supplement offered to dairy cows grazing pasture according to nutritional requirements in early lactation. [PDF]

JDS Commun
Ho CKM, Douglas ML, Giri K, Wales WJ, Russo VM.   +4 more
europepmc   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Nutritional requirements of buffaloes: A narrative review

In the wild, buffaloes (Bubalus bubalis) are divided into two categories: swamp buffalo (Carabao) and river buffalo (Murrah, Jafarabadi, Mediterranean).
Emanuel Isaque Cordeiro da Silva, Joanne Silvine Lourenço   +1 more
core   +1 more source

Recent Advances in Nutritional Requirements and Metabolic Homeostasis Regulation of Animals Under Stress Conditions. [PDF]

Animals (Basel)
Li X, Li X, Wu Z, Wang K, Qiao R, Han X, Li X, Yang F, Yu T, Wang T, Bai J.   +10 more
europepmc   +1 more source

Revealing nutritional requirements of MICP-relevant Sporosarcina pasteurii DSM33 for growth improvement in chemically defined and complex media. [PDF]

Sci Rep, 2020
Lapierre FM, Schmid J, Ederer B, Ihling N, Büchs J, Huber R.   +5 more
europepmc   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Cálculo das recomendações de ingestão protéica: aplicação a pré-escolar, escolar e adulto utilizando alimentos brasileiros

Revista de Saúde Pública
As recomendações de ingestão protéica variam conforme o teor de proteína, da quantidade de aminoácidos essenciais oferecidas e da digestibilidade da dieta.
J. Sérgio Marchini, Margareth M.P. Rodrigues, Selma F.C. Cunha, M. Arlene Fausto, Helio Vannucchi, J.E. Dutra de Oliveira   +5 more
doaj  

Drosophila-associated bacteria differentially shape the nutritional requirements of their host during juvenile growth. [PDF]

PLoS Biol, 2020
Consuegra J, Grenier T, Baa-Puyoulet P, Rahioui I, Akherraz H, Gervais H, Parisot N, da Silva P, Charles H, Calevro F, Leulier F.   +10 more
europepmc   +1 more source

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

Advanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu, Jiaqi Zou, Geng Han, Mengyao Zhao, Ting Luo, Xiangru Feng, Liangliang Zhu, Yijia Chen, Xiaoguo Ji, Jiayang Jin, Liming Zhao   +10 more
wiley   +1 more source