Results 131 to 140 of about 806,094 (302)

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min   +6 more
wiley   +1 more source

Traditional Nutritional Beliefs and Practices Among Mothers in Riyadh During the Puerperal Period: a Cross-Sectional Study

open access: yesInternational Journal of Women's Health
Anwar M Alhashem, Fay A Alrasheed, Latifa K Alwallan, Maram F Almutairi, Yara M Bin Khathran, Yasmeen A Alenzi, Rehab A Aldahash Department of Health Sciences, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University ...
Alhashem AM   +6 more
doaj  

Predictors of Growth Monitoring and Promotion Service Utilization Among Mothers With Children Aged 0–23 Months in Savelugu Municipality, Ghana

open access: yesAdvances in Public Health
Growth monitoring and promotion (GMP) service is one of the strategies to promote child health and reduce child mortality. However, there is limited data on predictors of GMP service utilization in Savelugu Municipality.
Ambrose Atosona   +5 more
doaj   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang   +17 more
wiley   +1 more source

Upregulated hepatic lipogenesis from dietary sugars in response to low palmitate feeding supplies brain palmitate

open access: yesNature Communications
Palmitic acid (PAM) can be provided in the diet or synthesized via de novo lipogenesis (DNL), primarily, from glucose. Preclinical work on the origin of brain PAM during development is scarce and contrasts results in adults.
Mackenzie E. Smith   +7 more
doaj   +1 more source

Labeling Requirements for Alaska Seafood Processors [PDF]

open access: yes, 2013
Alaska commercial seafood processors must label their product according to state and federal regulations. This bulletin makes clear what information is required—company name, name of seafood, ingredients (if applicable), permit number, date, weight, care
Chambers, Izetta
core  

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