Results 191 to 200 of about 5,195,387 (347)
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
Editorial: Nutrition in pancreatic diseases: the role of nutritional status and nutrition therapy in the management of pancreatitis and pancreatic cancer. [PDF]
Wiese ML, Perra T, Porcu A.
europepmc +1 more source
Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu +13 more
wiley +1 more source
Associations between food-related behaviours, nutrient intake and nutritional status through Structural Equation Model (SEM) among clients undergoing Community-Based Treatment and Rehabilitation (CBTaR): A cross-sectional study in Kelantan, Malaysia. [PDF]
Aji AS +8 more
europepmc +1 more source
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei +12 more
wiley +1 more source
The evidence base of supplementary feeding programmes and SBCC interventions on nutritional and behavioural outcomes globally: a scoping review protocol. [PDF]
Gupta N +12 more
europepmc +1 more source

