Results 61 to 70 of about 16,307,918 (298)

Cloned long-term cytolytic T-lymphocyte line with specificity for an immediate-early membrane antigen of murine cytomegalovirus [PDF]

, 1986
Long-term cytolytic T-lymphocyte (CTL) lines that are specific for distinct antigens associated with different phases of the replicative cycle of the murine cytomegalovirus (MCMV) were established by cloning of CTL lines derived from lymph nodes of ...
Reddehase, Matthias J., Koszinowski, Ulrich H., Bühring, Hans-Jörg   +2 more
core   +1 more source

Markers of intestinal infection agents in patients with acute viral hepatitis with cholestatic syndrome

Терапевтический архив, 2011
Aim. To study the pathogenetic role of agents of the most common intestinal infections in the development of cholestatic syndrome in patients with acute viral hepatitis. Material and methods.
Svetlana Nikolaevna Zuevskaya, Ol'ga Fedorovna Belaya, Elena Bacil'evna Volchkova, Natal'ya Alekseevna Andrekayte, S N Zuevskaya, O F Belaya, E V Volchkova, N A Andrekaite   +7 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Wzx flippases exhibiting complex O‐unit preferences require a new model for Wzx–substrate interactions

MicrobiologyOpen, 2019
The Wzx flippase is a critical component of the O‐antigen biosynthesis pathway, being responsible for the translocation of oligosaccharide O units across the inner membrane in Gram‐negative bacteria.
Michael A. Liu, Paraskevi Morris, Peter R. Reeves   +2 more
doaj   +1 more source

Genomic diversity and organization of complex polysaccharide biosynthesis clusters in the genus Dickeya.

PLoS ONE, 2021
The pectinolytic genus Dickeya (formerly Erwinia chrysanthemi) comprises numerous pathogenic species which cause diseases in various crops and ornamental plants across the globe.
Manish Ranjan, Devanshi Khokhani, Sanjeeva Nayaka, Suchi Srivastava, Zachary P Keyser, Ashish Ranjan   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Structure and genetics ofShigellaO antigens [PDF]

FEMS Microbiology Reviews, 2008
This review covers the O antigens of the 46 serotypes of Shigella, but those of most Shigella flexneri are variants of one basic structure, leaving 34 Shigella distinct O antigens to review, together with their gene clusters. Several of the structures and gene clusters are reported for the first time and this is the first such group for which ...
Bin, Liu, Yuriy A, Knirel, Lu, Feng, Andrei V, Perepelov, Sof'ya N, Senchenkova, Quan, Wang, Peter R, Reeves, Lei, Wang   +7 more
openaire   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Systems Biology and Pangenome of Salmonella O-Antigens

mBio, 2019
O-antigens are glycopolymers in lipopolysaccharides expressed on the cell surface of Gram-negative bacteria. Variability in the O-antigen structure constitutes the basis for the establishment of the serotyping schema. We pursued a two-pronged approach to
Yara Seif, Jonathan M. Monk, Henrique Machado, Erol Kavvas, Bernhard O. Palsson   +4 more
doaj   +1 more source

CLASSIFICATION OF PSEUDOMONAS AERUGINOSA O ANTIGENS BY IMMUNOELECTROPHORESIS [PDF]

Journal of Medical Microbiology, 1975
Heated saline extracts of 89 strains, and (1) supernates of phenol-water extracts (L1 fractions), (2) purified lipopolysaccharide, (3) trichloracetic-acid (TCA) extracts, and (4) sodium-hydroxide extracts of 23 strains representing all Pseudomonas aeruginosa O antigens were subjected electrophoresis.
B, Lányi, M M, Adám, A, Szentmihályi
openaire   +2 more sources