Results 101 to 110 of about 111,719 (284)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Conformance Testing of F1AP Protocol in 5G O-RAN

open access: yesIEEE Open Journal of the Communications Society
The rapid development of fifth-generation (5G) communication networks is driven not only by the standardization efforts of the 3rd Generation Partnership Project (3GPP), but also by the modular, interoperable design introduced by the Open Radio Access ...
Cheng-Feng Hung   +5 more
doaj   +1 more source

RRC Signaling Storm Detection in O-RAN

open access: yes
The Open Radio Access Network (O-RAN) marks a significant shift in the mobile network industry. By transforming a traditionally vertically integrated architecture into an open, data-driven one, O-RAN promises to enhance operational flexibility and drive innovation.
Nguyen, Dang Kien   +2 more
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Optimizing Energy Consumption for vRAN Placement in O-RAN Systems With Flexible Transport Networks

open access: yesIEEE Open Journal of the Communications Society
Virtualized RAN (vRAN) matches O-RAN Alliance specifications while transitioning towards virtualized functions on general-purpose computing platforms. However, the energy consumption of these systems remains a major concern.
William T. Pires-JR   +5 more
doaj   +1 more source

The Franks Flying Suit in Canadian Aviation Medicine History, 1939–1945 [PDF]

open access: yes, 2012
It is not widely appreciated that Canadians were active during the war in the field of aviation medicine. Aviation medicine research in Canada during the Second World War involved a significant commitment of personnel and resources.
Smith, George
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Bước đầu nghiên cứu đặc điểm hình thái, dinh dưỡng và sinh sản của rắn ráo thường- Ptyas Korros (Schlegel, 1837) ở vùng Đồng bằng sông Cửu Long

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2015
Bài báo này nhằm cung cấp những dẫn liệu khoa học về đặc điểm sinh học (các đặc điểm hình thái, dinh dưỡng và sinh sản) của loài rắn Ráo thường - Ptyas korros (Schlegel, 1837) ở khu vực Đồng bằng sông Cửu Long.
Hoàng Thị Nghiệp
doaj  

Following the Journey of Network Slicing in 5G and 5G Advanced: Essential Concepts, Key Operations, Lifecycle Management, and Future Enhancements

open access: yesIEEE Access
5G networks deliver services with faster speeds, higher capacity, lower latency and higher resilience. Network Slicing is one of the fundamental pillars for offering diverse services.
Rahul Varma Chintalapati   +2 more
doaj   +1 more source

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