Results 81 to 90 of about 1,110 (213)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

O-RAN Security: From Standardization and Threat Modeling to Practical Security Testing

IEEE Open Journal of the Communications Society
The Open Radio Access Network (O-RAN) introduces openness and disaggregation to cellular networks, enabling innovation and multi-vendor interoperability.
Joshua Moore, Aly Sabri Abdalla, Felix Klement, Aayam Raj Shakya, Prateek Shantharama, Vuk Marojevic   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Proactive AI-and-RAN Workload Orchestration in O-RAN Architectures for 6G Networks

IEEE Open Journal of the Communications Society
The vision of AI-RAN convergence, as advocated by the AI-RAN Alliance, aims to unlock a unified 6G platform capable of seamlessly supporting AI and RAN workloads over shared infrastructure.
Syed Danial Ali Shah, Maryam Hafeez, Abdelaziz Salama, Syed Ali Raza Zaidi   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

DRL-Based RAN Slicing With Efficient Inter-Slice Isolation in Tactical Wireless Networks

IEEE Open Journal of Vehicular Technology
The next generation of tactical networks (TNs) is poised to further leverage the key enablers of 5G and beyond 5G (B5G) technology, such as radio access network (RAN) slicing and the open RAN (O-RAN) paradigm, to unlock new architectural options for ...
Abderrahime Filali, Diala Naboulsi, Georges Kaddoum   +2 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Detecting Out-of-Order Control Messages in O-RAN: Dataset, Benchmarks, and Early-Warning Models

IEEE Open Journal of the Communications Society
The Open Radio Access Network (O-RAN) architecture introduces openness, programmability, and multi-vendor xApp innovation through the Near-Real-Time RAN Intelligent Controller (Near-RT RIC).
Hams Gelban, Rouaa Naim, Ahmed Badawy
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source