Results 61 to 70 of about 1,110 (213)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Intelligent O-RAN Beyond 5G: Architecture, Use Cases, Challenges, and Opportunities

IEEE Access
Open RAN (Radio Access Network) is revolutionizing the telecom space by introducing a framework based on the concepts of virtualization and openness.
Simona Marinova, Alberto Leon-Garcia
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Predicting Conflict Impact on Performance in O-RAN

IEEE INFOCOM 2026 - IEEE Conference on Computer Communications
INFOCOM 2026 Workshop - 6G AI-RAN: AI Native Distributed Intelligence for 6G Networks.
Pietro Brach del Prever, Niloofar Mohamadi, Salvatore D'Oro, Leonardo Bonati, Michele Polese, Lukasz Kulacz, Piotr Jaworski, Adrian Kliks, Heiko Lehmann, Tommaso Melodia   +9 more
openaire   +3 more sources

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Multi-UE 5G RAN Measurements: A Gamut of Architectural Options

IEEE Access
The Radio Access Network (RAN) of Fifth Generation (5G) communication systems critically influences the overall performance and cost of a 5G system.
Andreas Ingo Grohmann, Mauri Seidel, Sebastian A. W. Itting, Ray-Guang Cheng, Martin Reisslein, Frank H. P. Fitzek   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

TACIT: Trustworthy Arbitration Through Calibrated Inference Tracking for rApp Conflict Resolution in O-RAN

IEEE Access
Open Radio Access Network (O-RAN) deployments face a coordination challenge when multiple radio applications (rApps) concurrently propose conflicting parameter changes.
Joss Armstrong, Sheila Fallon, Enda Fallon   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Energy Consumption of Machine Learning Enhanced Open RAN: A Comprehensive Review

IEEE Access
The Open Radio Access Network (RAN) emerges as a revolutionary architecture promising unprecedented levels of openness, flexibility, and intelligence within radio access networks. Central to this innovation is the integration of Machine Learning (ML) and
Xuanyu Liang, Qiao Wang, Ahmed Al-Tahmeesschi, Swarna B. Chetty, David Grace, Hamed Ahmadi   +5 more
doaj   +1 more source