Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Toward Programmability of Radio Resource Control Based on O-RAN
Open Radio Access Network (O-RAN) is a concept that aims at embedding intelligence at the network edge and at disaggregating of network functionality from the hardware.
Pencheva Evelina N., Atanasov Ivaylo I.
doaj +1 more source
Change in Composition of the Anopheles Gambiae Complex and its Possible Implications for the Transmission of Malaria and Lymphatic Filariasis in North-Eastern Tanzania. [PDF]
A dramatic decline in the incidence of malaria due to Plasmodium falciparum infection in coastal East Africa has recently been reported to be paralleled (or even preceded) by an equally dramatic decline in malaria vector density, despite absence of ...
A Mahande +52 more
core +4 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Attacking O-RAN Interfaces: Threat Modeling, Analysis and Practical Experimentation
A new generation of open and disaggregated Radio Access Networks (RANs) enabling multi-vendor, flexible, and cost-effective deployments is being promoted by the Open Radio Access Network (O-RAN) Alliance.
Pau Baguer +6 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Organic Centre Wales Technical Note 2: Evaluation of Sárpo potato varieties, 2004 [PDF]
Potato blight Phytophora infestans is a major limiting factor on potato production and is a particular problem for organic growers in Wales. The use of blight resistant varieties is an important strategy in the management of late blight.
Anon
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
A Hybrid Zero Trust Deployment Model for Securing O-RAN Architecture in 6G Networks
The evolution toward sixth generation (6G) wireless networks promises higher performance, greater flexibility, and enhanced intelligence. However, it also introduces a substantially enlarged attack surface driven by open, disaggregated, and multi-vendor ...
Max Hashem Eiza +4 more
doaj +1 more source
Organic Centre Wales Factsheet 2: Information on the relationship between the Organic Farming Scheme and Tir Gofal [PDF]
This factsheet provides information on the relationship between the Organic Farming Scheme and Tir Gofal. Issues covered are; entering land into both schemes, payments, underlying principles of the schemes and arable ...
Anon
core

