Results 101 to 110 of about 1,110 (213)

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Towards secure intelligent O-RAN architecture: Vulnerabilities, threats and promising technical solutions using LLMs

Digital Communications and Networks
The evolution of wireless communication systems will be fundamentally impacted by an Open Radio Access Network (O-RAN), a new concept defining an intelligent architecture with enhanced flexibility, openness, and the ability to slice services more ...
Mojdeh Karbalaee Motalleb, Chafika Benzaid, Tarik Taleb, Marcos Katz, Vahid Shah-Mansouri, Jaeho Kim   +5 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Bước đầu nghiên cứu đặc điểm hình thái, dinh dưỡng và sinh sản của rắn ráo thường- Ptyas Korros (Schlegel, 1837) ở vùng Đồng bằng sông Cửu Long

Tạp chí Khoa học Đại học Cần Thơ, 2015
Bài báo này nhằm cung cấp những dẫn liệu khoa học về đặc điểm sinh học (các đặc điểm hình thái, dinh dưỡng và sinh sản) của loài rắn Ráo thường - Ptyas korros (Schlegel, 1837) ở khu vực Đồng bằng sông Cửu Long.
Hoàng Thị Nghiệp
doaj  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Toward Incorporating mmWave Beam Tracking for Connected Autonomous Vehicles

IEEE Access
As we move towards the Beyond 5G/6G era, the importance of Open Radio Access Network (Open RAN) is growing significantly. While traditional RAN systems are largely controlled by specific vendors, the O-RAN alliance promotes open interfaces to enable a ...
Jin Nakazato, Kazuki Maruta, Ryo Iwaki, Sojin Ozawa, Yuki Sasaki, Tetsuya Iye, Zongdian Li, Rui Dinis   +7 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Multi-Tier Hierarchical Intelligence for Joint RIS–NOMA Optimization in O-RAN-Enabled 6G Networks

IEEE Access
The evolution toward sixth-generation (6G) networks demands architectures that integrate intelligence, flexibility, and spectral efficiency beyond the limits of conventional fifth-generation (5G) systems.
Ahmed Abdelreheem, Aya Allah A. Elserwe, Ahmed H. Zahran, Mohamed Abdel-Nasser   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source