Results 51 to 60 of about 16,308,338 (297)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Tumor antigen cross-presentation and the dendritic cell: Where it all begins? [PDF]

, 2010
Dendritic cells (DCs) are professional antigen-presenting cells (APCs) that are critical for the generation of effective cytotoxic T lymphocyte (CTL) responses; however, their function and phenotype are often defective or altered in tumor-bearing hosts ...
McDonnell, A.M., Robinson, B.W.S., Currie, A.J.   +2 more
core  

Validation of electrochemiluminescent (ECL)-based immunoassay to determine the levels of antibodies against Escherichia coli O-lipopolysaccharide antigens

Microbiology Spectrum
Extra-intestinal pathogenic Escherichia coli (ExPEC) is a significant cause of invasive infections, including urinary tract infections, neonatal meningitis, and bacteremia.
Maanan Kamdar, Vichiksha Shah, Sarah Janssen, Elizabeth Garcia Dominguez, Todd Davies, Germie van den Dobbelsteen   +5 more
doaj   +1 more source

Convergent synthesis of the tetrasaccharide repeating unit of the O-antigen of Shigella boydii type 9

Beilstein Journal of Organic Chemistry, 2011
A convenient synthesis of the tetrasaccharide repeating unit of the O-antigen of Shigella boydii type 9 has been achieved in excellent yield using a [2 + 2] block glycosylation strategy.
Abhishek Santra, Anup Kumar Misra
doaj   +1 more source

Strain Selection for Generation of O-Antigen-Based Glycoconjugate Vaccines against Invasive Nontyphoidal Salmonella Disease. [PDF]

PLoS ONE, 2015
Nontyphoidal Salmonellae, principally S. Typhimurium and S. Enteritidis, are a major cause of invasive bloodstream infections in sub-Saharan Africa with no vaccine currently available.
Luisa Lanzilao, Giuseppe Stefanetti, Allan Saul, Calman A MacLennan, Francesca Micoli, Simona Rondini   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation [PDF]

, 2019
Two Shigella species, flexneri and sonnei, cause approximately 90% of bacterial dysentery worldwide. While S. flexneri is the dominant species in low-income countries, S. sonnei causes the majority of infections in middle and high-income countries.
Goddard, Philippa J., Shenoy, Avinash R., Abigail Clements, Shenoy, Avinash R, Serge Mostowy, Mostowy, Serge, Philippa J. Goddard, Goddard, Philippa J, Torraca, V., Watson, Jayne, Clements, Abigail, Jayne L. Watson, Avinash R. Shenoy, Watson, Jayne L., Torraca, Vincenzo, Shenoy, Avinash, Julia Sanchez-Garrido, Sanchez-garrido, Julia, Goddard, Philippa, Watson, Jayne L, Vincenzo Torraca   +20 more
core   +1 more source

The normal chain length distribution of the O antigen is required for the interaction of Shigella flexneri 2a with polarized Caco-2 cells

Biological Research, 2012
Shigella flexneri causes bacillary dysentery in humans. Essential to the establishment of the disease is the invasion of the colonic epithelial cells. Here we investigated the role of the lipopolysaccharide (LPS) O antigen in the ability of S.
Anilei Hoare, Denisse Bravo, Mara Martinic, Miguel A Valvano, Inés Contreras, Sergio A Álvarez   +5 more
doaj  

Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4

Beilstein Journal of Organic Chemistry, 2014
The pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4 strain has been synthesized using a combination of sequential glycosylations and [3 + 2] block synthetic strategy from the suitably protected monosaccharide intermediates ...
Pintu Kumar Mandal
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source