Results 21 to 30 of about 15,529,870 (301)

Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4 [PDF]

, 2010
Schistosoma haematobium antigen recognition profiles of the human isotypes IgA, IgE, IgG1 and IgG4 were compared by image analysis of western blots. Adult worm antigens separated by 2-dimensional gel electrophoresis were probed with pooled sera from ...
Midzi, N., Maizels, R M, Burchmore, R., Y. HARCUS, Mduluza, T., R. M. MAIZELS, Harcus, Y, Turner, C.M.R., R. BURCHMORE, C. M. TURNER, Mutapi, F, Midzi, N, Mutapi, F., Maizels, R.M., Turner, C M, Maizels, RM, N. MIDZI, Harcus, Y., Bourke, C., F. MUTAPI, T. MDULUZA, Turner, CM, Maizels, R. M., Bourke, C, Turner, C. M., Mduluza, T, Burchmore, R.J.S., Burchmore, R, C. BOURKE   +28 more
core   +1 more source

Lipophilic O-antigens in Rhodospirillum tenue [PDF]

Journal of Bacteriology, 1977
Lipopolysaccharides of eight wild-type strains of the phototrophic bacterium Rhodospirillum tenue have been analyzed. All of the lipopolysaccharides are highly lipophilic. The compositions of preparations obtained by the phenol-water or by the phenol-chloroform-petroleum ether procedure are very similar. The polysaccharide moiety, obtained by mild acid
J, Weckesser, G, Drews, R, Indira, H, Mayer   +3 more
openaire   +2 more sources

Role of O-Acetylation in the Immunogenicity of Bacterial Polysaccharide Vaccines

Molecules, 2018
The incidence of infectious diseases caused by several bacterial pathogens such as Haemophilus influenzae type b, Streptococcus pneumoniae, and Neisseria meningitidis, has been dramatically reduced over the last 25 years through the use of glycoconjugate
Francesco Berti, Riccardo De Ricco, Rino Rappuoli   +2 more
doaj   +1 more source

The HLA Ligandome Comprises a Limited Repertoire of O-GlcNAcylated Antigens Preferentially Associated With HLA-B*07:02

Frontiers in Immunology, 2021
Mass-spectrometry based immunopeptidomics has provided unprecedented insights into antigen presentation, not only charting an enormous ligandome of self-antigens, but also cancer neoantigens and peptide antigens harbouring post-translational ...
Soumya Mukherjee, Soumya Mukherjee, Alvaro Sanchez-Bernabeu, Alvaro Sanchez-Bernabeu, Laura C. Demmers, Laura C. Demmers, Wei Wu, Wei Wu, Albert J. R. Heck, Albert J. R. Heck   +9 more
doaj   +1 more source

Identification of protective antigens for vaccination against systemic salmonellosis [PDF]

, 2014
There is an urgent medical need for improved vaccines with broad serovar coverage and high efficacy against systemic salmonellosis. Subunit vaccines offer excellent safety profiles but require identification of protective antigens, which remains a ...
Dirk eBumann, Bumann, Dirk, Dirk Bumann, Bumann D   +3 more
core   +1 more source

Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface

Nature Communications, 2020
The O-antigen of LPS is known to limit the binding of antibody to bacterial surface antigens. Here the AUs show that the chemical and physical structure of the O-antigen are central factors in limiting the exposure of surface antigens to antibodies ...
C. Coral Domínguez-Medina, Marisol Pérez-Toledo, Anna E. Schager, Jennifer L. Marshall, Charlotte N. Cook, Saeeda Bobat, Hyea Hwang, Byeong Jae Chun, Erin Logan, Jack A. Bryant, Will M. Channell, Faye C. Morris, Sian E. Jossi, Areej Alshayea, Amanda E. Rossiter, Paul A. Barrow, William G. Horsnell, Calman A. MacLennan, Ian R. Henderson, Jeremy H. Lakey, James C. Gumbart, Constantino López-Macías, Vassiliy N. Bavro, Adam F. Cunningham   +23 more
doaj   +1 more source

Stable Chromosomal Expression of Shigella flexneri 2a and 3a O-Antigens in the Live Salmonella Oral Vaccine Vector Ty21a. [PDF]

Clin Vaccine Immunol, 2017
We have been exploring the use of the live attenuated Salmonella enterica serovar Typhi Ty21a vaccine strain as a versatile oral vaccine vector for the expression and delivery of multiple foreign antigens, including ...
Dharmasena MN, Osorio M, Takeda K, Stibitz S, Kopecko DJ.   +4 more
europepmc   +2 more sources

Comparison of schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections [PDF]

, 2011
A Schistosoma mansoni cercarial antigen preparation (cercarial transformation fluid – SmCTF) was evaluated for detection of anti-schistosome antibodies in human sera in 4 collaborating laboratories.
Dawson, E., Smith, H., Ji, Minjun, Mike Doenhoff, Emily Dawson, Claire Alexander, Gilis, Henk, van Gool, T., Cara Aitken (135264), Grant Spence, Aitken, Cara, Aitken, C., Bailey, W., Cara Aitken, Minjun Ji (135275), Spence, G., Spence, Grant, Henk Gilis, Tom van Gool, Doenhoff, M., Claire Alex, Wendi Bailey, Mike Doenhoff (135259), Gilis, H., Huw Smith, Doenhoff, Mike, van Gool, Tom, Dawson, Emily, Smith, Huw, Tom van Gool (135295), Henk Gilis (135283), Claire Alexander (20985), Minjun Ji, Bailey, Wendi, Grant Spence (135288), Alexander, C., Ji, M., Huw Smith (135256), Wendi Bailey (135270), Emily Dawson (135279), Alexander, Claire, van Gool Tom, Spence Grant, Smith Huw, Gilis Henk, Aitken Cara, Bailey Wendi, Alexander Claire, Ji Minjun, Doenhoff Mike, Dawson Emily   +50 more
core   +2 more sources

Mechanism of O-antigen distribution in lipopolysaccharide [PDF]

Journal of Bacteriology, 1990
O-antigen units are nonuniformly distributed among lipid A-core molecules in lipopolysaccharide (LPS) from gram-negative bacteria, as revealed by polyacrylamide gel electrophoresis in sodium dodecyl sulfate; the actual distribution patterns are complex, multimodal, and strain specific.
R C, Goldman, F, Hunt
openaire   +2 more sources

Is indirect coombs test by pooled cells sufficient for antibody screening? An eye-opening case series

Global Journal of Transfusion Medicine, 2023
The ideal way to screen for the presence of alloantibodies is by antibody screening panels which represent all clinically significant antigens in appropriate dosage.
P Sriraman, Dibyajyoti Sahoo, Abhishekh Basavarajegowda, Shahida Noushad, Esha Toora, Rajendra G Kulkarni   +5 more
doaj   +1 more source