Results 21 to 30 of about 207,539 (163)

Questioning universal use of O– red blood cells in intrauterine transfusions

AJOG Global Reports, 2023
In the setting of maternal alloimmunization to antigen(s) on fetal red blood cells, significant fetal anemia may develop, and an intrauterine transfusion may be required. When selecting a blood product for intrauterine transfusion, the priority should be
Olivia G. Johnson, BS, William N. Rose, MD   +1 more
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Identification of the lipopolysaccharide O‐antigen biosynthesis priming enzyme and the O‐antigen ligase in Myxococcus xanthus: critical role of LPS O‐antigen in motility and development [PDF]

Molecular Microbiology, 2019
SummaryMyxococcus xanthus is a model bacterium to study social behavior. At the cellular level, the different social behaviors of M. xanthus involve extensive cell–cell contacts. Here, we used bioinformatics, genetics, heterologous expression and biochemical experiments to identify and characterize the key enzymes in M.
María Pérez‐Burgos, Inmaculada García‐Romero, Jana Jung, Miguel A. Valvano, Lotte Søgaard‐Andersen   +4 more
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The identification of novel immunogenic antigens as potential Shigella vaccine components

Genome Medicine, 2021
Background Shigella is a major diarrheal pathogen for which there is presently no vaccine. Whole genome sequencing provides the ability to predict and derive novel antigens for use as vaccines.
Ruklanthi de Alwis, Li Liang, Omid Taghavian, Emma Werner, Hao Chung The, Trang Nguyen Hoang Thu, Vu Thuy Duong, D. Huw Davies, Philip L. Felgner, Stephen Baker   +9 more
doaj   +1 more source

Development of a Potent Stabilizer for Long-Term Storage of Foot-and-Mouth Disease Vaccine Antigens

Vaccines, 2021
A local virus isolate, O/SKR/JC/2014 (O JC), has been considered as a candidate vaccine strain in the development of a domestic foot-and-mouth disease (FMD) vaccine in Korea.
Ah-Young Kim, Hyejin Kim, Sun Young Park, Sang Hyun Park, Jae-Seok Kim, Jung-Won Park, Jong-Hyeon Park, Young-Joon Ko   +7 more
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Preparation of human monoclonal anti-C cell line from peripheral blood B lymphocytes of D--donor

Zhongguo shuxue zazhi, 2022
Objective To establish human hybridoma cell lines, secreting monoclonal antibody against antigens of Rh blood system, from a donor with rare D--phenotype.
Zhonghui GUO, Fengyong ZHAO, Demei ZHANG, Dong XIANG, Jiamin ZHANG, Ying YANG, Qin LI, Qixiu YANG, Chen WANG, Ziyan ZHU   +9 more
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Toward a Multivalent Synthetic Oligosaccharide-Based Conjugate Vaccine against Shigella: State-of-the-Art for a Monovalent Prototype and Challenges

Vaccines, 2022
This review focuses on the molecular glycovaccine concept, a promising option to develop a Shigella glycoconjugate vaccine. Subsequent to original developments involving, as main vaccine component, the detoxified Shigella lipopolysaccharide randomly ...
Armelle Phalipon, Laurence A. Mulard
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Mucin-Type O-Glycosylation in Gastric Carcinogenesis

Biomolecules, 2016
Mucin-type O-glycosylation plays a crucial role in several physiological and pathological processes of the gastric tissue. Modifications in enzymes responsible for key glycosylation steps and the consequent abnormal biosynthesis and expression of their ...
Henrique O. Duarte, Daniela Freitas, Catarina Gomes, Joana Gomes, Ana Magalhães, Celso A. Reis   +5 more
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A Sweet Warning: Mucin-Type O-Glycans in Cancer

Cells, 2022
Glycosylation is a common post-translational modification process of proteins. Mucin-type O-glycosylation is an O-glycosylation that starts from protein serine/threonine residues.
Yuhan Zhang, Lingbo Sun, Changda Lei, Wenyan Li, Jiaqi Han, Jing Zhang, Yuecheng Zhang   +6 more
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Inter-individual and inter-regional variability of breast milk antibody reactivity to bacterial lipopolysaccharides

Frontiers in Immunology
Breast milk is a vital source of nutrients, prebiotics, probiotics, and protective factors, including antibodies, immune cells and antimicrobial proteins. Using bacterial lipopolysaccharide arrays, we investigated the reactivity and specificity of breast
Lisa Crone, Jens Sobek, Nicole Müller, Tanja Restin, Tanja Restin, Dirk Bassler, Daniela Paganini, Michael B. Zimmermann, Patricia Zarnovican, Françoise H. Routier, Tais Romero-Uruñuela, Luis Izquierdo, Luis Izquierdo, Thierry Hennet   +13 more
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The Antigenic Structure Characterization of Oestrus Ovis Larvae

Scientific Papers Animal Science and Biotechnologies, 2023
With the aim of proteic components definition from Oestrus ovis larvae, endowed with antigenic properties, able to induce immune responses in vivo and to react in vitro with induced molecular effectors were been performed: electrophoresis in ...
Daniela Moţ
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