Results 41 to 50 of about 15,529,870 (301)

Studies on in vitro human T cell reactivity to antigens of mycobacterium tuberculosis [PDF]

, 2010
Studies on Mycobacterium tuberculosis (MTB) antigens are important to improve immunodiagnostics and vaccine efficacy. A novel genome based strategy for antigen discovery is to relate what is highly expressed by bacilli in vivo or in vitro, to what is ...
Gideon, Hannah Priyadarshini
core   +1 more source

Immunoblot analysis of the seroreactivity to recombinant Borrelia burgdorferi sensu lato antigens, including VlsE, in the long-term course of treated patients with Erythema migrans [PDF]

, 2008
Objective: We evaluated whether immunoblotting is capable of substantiating the posttreatment clinical assessment of patients with erythema migrans ( EM), the hallmark of early Lyme borreliosis.
Glatz, Martin, Wilske, Bettina, Fingerle, Volker, Kerl, Helmut, Muellegger, Robert R., Ambros-Rudolph, Christina   +5 more
core   +1 more source

Exploring the immunology of parasitism--from surface antigens to the hygiene hypothesis [PDF]

, 2009
Helminth immunology is a field which has changed beyond recognition in the past 30 years, transformed not only by new technologies from cDNA cloning to flow cytometry, but also conceptually as our definition of host immune pathways has matured.
R. M. MAIZELS, Maizels, R M
core   +1 more source

Mucin-Type O-Glycosylation in Gastric Carcinogenesis

Biomolecules, 2016
Mucin-type O-glycosylation plays a crucial role in several physiological and pathological processes of the gastric tissue. Modifications in enzymes responsible for key glycosylation steps and the consequent abnormal biosynthesis and expression of their ...
Henrique O. Duarte, Daniela Freitas, Catarina Gomes, Joana Gomes, Ana Magalhães, Celso A. Reis   +5 more
doaj   +1 more source

Toward a Multivalent Synthetic Oligosaccharide-Based Conjugate Vaccine against Shigella: State-of-the-Art for a Monovalent Prototype and Challenges

Vaccines, 2022
This review focuses on the molecular glycovaccine concept, a promising option to develop a Shigella glycoconjugate vaccine. Subsequent to original developments involving, as main vaccine component, the detoxified Shigella lipopolysaccharide randomly ...
Armelle Phalipon, Laurence A. Mulard
doaj   +1 more source

Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. [PDF]

, 2008
BACKGROUND: The asexual blood stages of the human malaria parasite Plasmodium falciparum produce highly immunogenic polymorphic antigens that are expressed on the surface of the host cell.
Christopher J. Drakeley, Saeed Maha, Saeed, Maha, Alexander Neal, Saeed, M., Geoffrey A T Targett, Sutherland, Colin J, Drakeley Christopher J., Targett Geoffrey A. T., Roeffen Will, Geoffrey A. T. Targett, Colin J. Sutherland, Targett, Geoffrey AT, Alexander, N., Neal Alexander, Colin J Sutherland, Sutherland Colin J., Targett, G.A.T., Roeffen, W.F.G., Roeffen, Will, Maha Saeed, Alexander, Neal, Drakeley, Christopher J, Drakeley, C., Will Roeffen, Christopher J Drakeley, Sutherland, C.J.   +26 more
core   +1 more source

A Sweet Warning: Mucin-Type O-Glycans in Cancer

Cells, 2022
Glycosylation is a common post-translational modification process of proteins. Mucin-type O-glycosylation is an O-glycosylation that starts from protein serine/threonine residues.
Yuhan Zhang, Lingbo Sun, Changda Lei, Wenyan Li, Jiaqi Han, Jing Zhang, Yuecheng Zhang   +6 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Systematic chemoenzymatic synthesis of O -sulfated sialyl Lewis x antigens [PDF]

, 2016
O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Tasnima, Nova, Chen, Xi, Louie, Angelique Y, Muthana, Musleh M, Li, Yanhong, Santra, Abhishek, Zeng, Jie, Yu, Hai, Kenyond, Nicholas J   +8 more
core   +1 more source

RDFization of E.coli O-antigen

, 2021
csv file and python code for RDFization of E.coli O-antigens in tabular data format.
Sunmyoung Lee, Kiyoko Kinoshita, Ono Tamiko   +2 more
openaire   +3 more sources