Results 61 to 70 of about 214,059 (308)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Differences in affinity of monoclonal and naturally acquired polyclonal antibodies against Plasmodium falciparum merozoite antigens [PDF]

, 2015
Malaria is a major global cause of deaths and a vaccine is urgently needed.; We have employed the P. falciparum merozoite antigens MSP2-3D7/FC27 and AMA1, used them in ELISA, and coupled them in different ways using surface plasmon resonance (SPR) and ...
Stanisic, Danielle, Kironde, Fred, Danielle I. Stanisic, Anders, Robin F, Reddy, Sreenivasulu B, Persson, Kristina, Sreenivasulu B. Reddy, Cross, Nadia, Mats Wahlgren, Anders, Robin F., Cross, N, Beeson, James G, Wahlgren, M, Senn, Nicolas, Senn, N, Nicolas Senn, Kristina E.M. Persson, Reddy, SB, Stanisic, DI, Wahlgren, Mats, Nadia Cross, Fred Kironde, Beeson, JG, Persson, KEM, Mueller, Ivo, Reddy, Sreenivasulu B., Ivo Mueller, Peter M. Siba, Kironde, F, Siba, Peter M, Mueller, I, Siba, PM, Stanisic, Danielle I, Stanisic, Danielle I., Persson, Kristina,, Robin F. Anders, James G. Beeson, Siba, Peter M., Persson, Kristina E. M., Lund University., Beeson, James G., Anders, RF   +41 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

O-Antigen Gene Clusters of Plesiomonas shigelloides Serogroups and Its Application in Development of a Molecular Serotyping Scheme

Frontiers in Microbiology, 2019
Plesiomonas shigelloides is a Gram-negative, flagellated, rod-shaped, ubiquitous, and facultative anaerobic bacterium. It has been isolated from various sources, such as freshwater, surface water, and many wild and domestic animals. P.
Daoyi Xi, Daoyi Xi, Daoyi Xi, Daoyi Xi, Xiaochen Wang, Xiaochen Wang, Xiaochen Wang, Xiaochen Wang, Kexin Ning, Kexin Ning, Kexin Ning, Kexin Ning, Qian Liu, Qian Liu, Qian Liu, Qian Liu, Fuyi Jing, Fuyi Jing, Fuyi Jing, Fuyi Jing, Xi Guo, Xi Guo, Xi Guo, Xi Guo, Boyang Cao, Boyang Cao, Boyang Cao, Boyang Cao   +27 more
doaj   +1 more source

RH phenotype, ABO and kell antigens, alleles and haplotypes frequencies in North Indian blood donor population

Global Journal of Transfusion Medicine, 2021
Background and Objectives: ABO, RH and Kell blood group systems are clinically significant blood group systems among 36 blood group systems having total of 360 blood group antigens which cause most cases of alloimmunization following blood transfusions ...
Sadhana Mangwana, Nikhil Simon, Lalitesh Sangwan   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

RDFization of E.coli O-antigen

, 2021
csv file and python code for RDFization of E.coli O-antigens in tabular data format.
Sunmyoung Lee, Kiyoko Kinoshita, Ono Tamiko   +2 more
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Systematic chemoenzymatic synthesis of O -sulfated sialyl Lewis x antigens [PDF]

, 2016
O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Tasnima, Nova, Chen, Xi, Kenyon, Nicholas J, Louie, Angelique Y, Muthana, Musleh M, Li, Yanhong, Santra, Abhishek, Kenyond, Nicholas J, Zeng, Jie, Yu, Hai   +9 more
core   +1 more source

How to select appropriate human-derived antiserum for absorption and elution test

Zhongguo shuxue zazhi
[Objective] To explore the importance of selecting appropriate human antiserum for absorption and elution tests by analyzing two cases in which weak A antigens were detected using this method. [Methods] The microcolumn agglutination and tube methods were
CHEN Dandan, LI Xiaoyan, ZENG Xuan
doaj   +1 more source