Results 91 to 100 of about 2,031 (173)

Substrate Dependent Alterations of Organic Anion Transporting Polypeptide 1B3 (OATP1B3) [PDF]

, 2011
Organic anion transporting polypeptides (OATPs) are multispecific transporters that mediate the uptake of numerous drugs and xenobiotics into cells.
Roth, Megan Elizabeth
core  

Uptake Transporters at the Blood-Brain Barrier and Their Role in Brain Drug Disposition. [PDF]

Pharmaceutics, 2023
Parvez MM, Sadighi A, Ahn Y, Keller SF, Enoru JO.   +4 more
europepmc   +1 more source

Corrigendum: The influence of physiological and pathological perturbations on blood-brain barrier function. [PDF]

Front Neurosci, 2023
Zhao N, Chung TD, Guo Z, Jamieson JJ, Liang L, Linville RM, Pessell AF, Wang L, Searson PC.   +8 more
europepmc   +1 more source

Implications of interactions between tyrosine kinase inhibitors and human solute carriers in cancer therapy [PDF]

, 2014
Members of the solute carrier (SLC) family of transporters govern the cellular influx of a multitude of endogenous compounds, xenobiotics and drugs. SLCs including organic anion transporting polypeptide (OATP) 1A2 (SLCO1A2), OATP1B3 (SLCO1B3) and organic
Johnston, Rosie Arwen
core  

Interaction of mycotoxins zearalenone, α-zearalenol, and β-zearalenol with cytochrome P450 (CYP1A2, 2C9, 2C19, 2D6, and 3A4) enzymes and organic anion transporting polypeptides (OATP1A2, OATP1B1, OATP1B3, and OATP2B1)

Toxicology in Vitro
Zearalenone (ZEN) is a mycoestrogen produced by Fusarium fungi. ZEN is a frequent contaminant in cereal-based products, representing significant health threat. The major reduced metabolites of ZEN are α-zearalenol (α-ZEL) and β-zearalenol (β-ZEL). Since the toxicokinetic interactions of ZEN/ZELs with cytochrome P450 enzymes (CYPs) and organic anion ...
Kaci, Hana, Dombi, Ágnes, Gömbös, Patrik, Szabó, András, Bakos, Éva, Özvegy-Laczka, Csilla, Poór, Miklós   +6 more
openaire   +3 more sources

Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters. [PDF]

Int J Mol Sci, 2023
Bakos É, Temesszentandrási-Ambrus C, Özvegy-Laczka C, Gáborik Z, Sarkadi B, Telbisz Á.   +5 more
europepmc   +1 more source

INTERACTION OF BAICALIN WITH TRANSPORTERS [PDF]

, 2017
Kalaposné Kovács Bernadett
core   +1 more source

Unique expression features of cancer-type organic anion transporting polypeptide 1B3 mRNA expression in human colon and lung cancers [PDF]

, 2014

core   +1 more source

No major effects of vitamin D (1,25 dihydroxyvitamin D) on absorption and pharmacokinetics of folic acid and fexofenadine in healthy volunteers [PDF]

core   +1 more source

Contribution of organic anion transporting polypeptides to bile acid uptake in the Caco-2 cell monolayer and gastrointestinal tract. [PDF]

J Biol Chem
Kurobe-Takashima Y, Yanagisawa K, Saito Y, Miyawaki R, Misaka T, Mizoi J, Miyauchi E, Sasaki N, Ogihara T, Kobayashi S.   +9 more
europepmc   +1 more source