Results 81 to 90 of about 2,031 (173)

Supplemental Figure Legends from Influence of Human OATP1B1, OATP1B3, and OATP1A2 on the Pharmacokinetics of Methotrexate and Paclitaxel in Humanized Transgenic Mice

open access: yes, 2023
<p>PDF file - 76K,Supplementary Figure legends</p>
Alfred H. Schinkel   +4 more
openaire   +1 more source

Supplemental Table 1 from Influence of Human OATP1B1, OATP1B3, and OATP1A2 on the Pharmacokinetics of Methotrexate and Paclitaxel in Humanized Transgenic Mice

open access: yes, 2023
<p>PDF file - 101K, Tabular RT-PCR analysis results about the expression of other transporter proteins in livers of knockout and humanized transgenic OATP mice</p>
Alfred H. Schinkel   +4 more
openaire   +1 more source

Microcystines : intoxication des animaux domestiques et sécurité des aliments d’origine animale [PDF]

open access: yes, 2007
Les cyanobactéries sont des micro-organismes ubiquistes qui se développent généralement dans les eaux douces. A cause de certaines caractéristiques, par exemple leur couleur bleu-vert et la présence de chlorophylle a, elles sont improprement appelées ...
Jaeg, Jean-Philippe
core  

Regulation of scaffold protein PDZK1 and its impact on the drug transporter OATP2B1 [PDF]

open access: yes, 2018
The PDZ domain containing 1 (PDZK1) is a scaffold and PDZ protein of the Na+/H +exchanger regulatory factor (NHERF) family. PDZ proteins consist of one or more PDZ domains that recognizes specific amino acid sequences at the C-terminus of membrane ...
Ferreira, Célio José
core   +1 more source

Association of Pharmacogenetic Markers with Premature Discontinuation of First-line Anti-HIV Therapy: An Observational Cohort Study [PDF]

open access: yes, 2017
Background. Poor tolerance and adverse drug reactions are main reasons for discontinuation of antiretroviral therapy (ART). Identifying predictors of ART discontinuation is a priority in HIV care. Methods.
Bernasconi, Enos   +12 more
core  

FEXOFENADINE AND ORGANIC ANION TRANSPORTING POLYPEPTIDES (OATPs): TRANSPORT AND DRUG-DRUG INTERACTIONS [PDF]

open access: yes, 2011
Transporters play a major role in the absorption and disposition of fexofenadine, suggesting this drug could be used as a probe of transporter activity.
Flynn, Colleen A.
core  

MOLECULAR AND FUNCTIONAL INVESTIGATION OF CANCER-TYPE AND LIVER-TYPE VARIANTS OF ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B3 [PDF]

open access: yes, 2015
OATP1B3 belongs to the OATP (organic anion transporting polypeptides) superfamily, responsible for mediating the transport of various endogenous and xenobiotic substrates.
Thakkar, Nilay
core   +1 more source

Exploring Possible Roles Of Organic Anion-Transporting Polypeptides In Invadopodia Function [PDF]

open access: yes, 2016
Drug resistant, invasive tumors are among the most devastating cancers. It is the goal of this project to explore the potential relationships between these two phenotypes in a variety of tissue culture model systems.
NC DOCKS at Appalachian State University   +1 more
core  

A Modified Grapefruit Juice Eliminates Two Compound Classes as Major Mediators of the Grapefruit Juice–Fexofenadine Interaction: An In Vitro–In Vivo “Connect” [PDF]

open access: yes, 2013
The grapefruit juice (GFJ)–fexofenadine interaction involves inhibition of intestinal organic anion transporting polypeptide (OATP)-mediated uptake. Only naringin has been shown clinically to inhibit intestinal OATP; other constituents have not been ...
NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

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