<p>PDF file - 76K,Supplementary Figure legends</p>
Alfred H. Schinkel +4 more
openaire +1 more source
<p>PDF file - 101K, Tabular RT-PCR analysis results about the expression of other transporter proteins in livers of knockout and humanized transgenic OATP mice</p>
Alfred H. Schinkel +4 more
openaire +1 more source
Microcystines : intoxication des animaux domestiques et sécurité des aliments d’origine animale [PDF]
Les cyanobactéries sont des micro-organismes ubiquistes qui se développent généralement dans les eaux douces. A cause de certaines caractéristiques, par exemple leur couleur bleu-vert et la présence de chlorophylle a, elles sont improprement appelées ...
Jaeg, Jean-Philippe
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Regulation of scaffold protein PDZK1 and its impact on the drug transporter OATP2B1 [PDF]
The PDZ domain containing 1 (PDZK1) is a scaffold and PDZ protein of the Na+/H +exchanger regulatory factor (NHERF) family. PDZ proteins consist of one or more PDZ domains that recognizes specific amino acid sequences at the C-terminus of membrane ...
Ferreira, Célio José
core +1 more source
Association of Pharmacogenetic Markers with Premature Discontinuation of First-line Anti-HIV Therapy: An Observational Cohort Study [PDF]
Background. Poor tolerance and adverse drug reactions are main reasons for discontinuation of antiretroviral therapy (ART). Identifying predictors of ART discontinuation is a priority in HIV care. Methods.
Bernasconi, Enos +12 more
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FEXOFENADINE AND ORGANIC ANION TRANSPORTING POLYPEPTIDES (OATPs): TRANSPORT AND DRUG-DRUG INTERACTIONS [PDF]
Transporters play a major role in the absorption and disposition of fexofenadine, suggesting this drug could be used as a probe of transporter activity.
Flynn, Colleen A.
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MOLECULAR AND FUNCTIONAL INVESTIGATION OF CANCER-TYPE AND LIVER-TYPE VARIANTS OF ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B3 [PDF]
OATP1B3 belongs to the OATP (organic anion transporting polypeptides) superfamily, responsible for mediating the transport of various endogenous and xenobiotic substrates.
Thakkar, Nilay
core +1 more source
Exploring Possible Roles Of Organic Anion-Transporting Polypeptides In Invadopodia Function [PDF]
Drug resistant, invasive tumors are among the most devastating cancers. It is the goal of this project to explore the potential relationships between these two phenotypes in a variety of tissue culture model systems.
NC DOCKS at Appalachian State University +1 more
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Molecular Mechanisms of Organic Anion Transporting Polypeptide-Mediated Organic Anion Clearance at the Blood-Cerebrospinal Fluid Barrier. [PDF]
Sun A, Hagenbuch B, Kelly EJ, Wang J.
europepmc +1 more source
A Modified Grapefruit Juice Eliminates Two Compound Classes as Major Mediators of the Grapefruit Juice–Fexofenadine Interaction: An In Vitro–In Vivo “Connect” [PDF]
The grapefruit juice (GFJ)–fexofenadine interaction involves inhibition of intestinal organic anion transporting polypeptide (OATP)-mediated uptake. Only naringin has been shown clinically to inhibit intestinal OATP; other constituents have not been ...
NC DOCKS at The University of North Carolina at Greensboro +1 more
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