Results 81 to 90 of about 1,270 (136)

Interaction of Methotrexate with Organic-Anion Transporting Polypeptide 1A2 and Its Genetic Variants

, 2020
Methotrexate (MTX) is used in patients with malignant and autoimmune diseases. This drug is primarily excreted unchanged in the urine, and its net excretion occurs via active secretory and reabsorptive processes.
T E F, S J J, M K
core  

Putative Modulation of OATP1A2 and P-gp Expression at the Blood-Brain Barrier by Nrf2-PXR: An Associative Hypothesis for Amyloid-β Transport in Alzheimer's Disease. [PDF]

Int J Mol Sci
Li L, Zhang Y, Li S, Zhao M, Hu W, Xiao Y, Wen J.   +6 more
europepmc   +1 more source

Uptake Transporters at the Blood-Brain Barrier and Their Role in Brain Drug Disposition. [PDF]

Pharmaceutics, 2023
Parvez MM, Sadighi A, Ahn Y, Keller SF, Enoru JO.   +4 more
europepmc   +1 more source

Corrigendum: The influence of physiological and pathological perturbations on blood-brain barrier function. [PDF]

Front Neurosci, 2023
Zhao N, Chung TD, Guo Z, Jamieson JJ, Liang L, Linville RM, Pessell AF, Wang L, Searson PC.   +8 more
europepmc   +1 more source

Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters. [PDF]

Int J Mol Sci, 2023
Bakos É, Temesszentandrási-Ambrus C, Özvegy-Laczka C, Gáborik Z, Sarkadi B, Telbisz Á.   +5 more
europepmc   +1 more source

Contribution of organic anion transporting polypeptides to bile acid uptake in the Caco-2 cell monolayer and gastrointestinal tract. [PDF]

J Biol Chem
Kurobe-Takashima Y, Yanagisawa K, Saito Y, Miyawaki R, Misaka T, Mizoi J, Miyauchi E, Sasaki N, Ogihara T, Kobayashi S.   +9 more
europepmc   +1 more source

Risk genes in progressive supranuclear palsy (PSP) affect integrity and function of microtubules. [PDF]

Front Aging
Donlon TA, Müller U.
europepmc   +1 more source

Insights and perspectives into the etiology of TKI-induced cardiotoxicity. [PDF]

ASPET Discov
Xu V, Ahmed B, Boleslav B, Mager DE, Sparreboom A, Sprowl JA, Huang KM.   +6 more
europepmc   +1 more source

<i>In Vitro</i> Evaluation of the Potential Interactions of Zearalenone-14-sulfate and Zearalenone-14-glucuronide with Human Cytochrome P450 Enzymes, Organic Anion Transporting Polypeptides, and ATP-Binding Cassette Multidrug Transporters. [PDF]

ACS Omega
Telbisz Á, Kaci H, Bakos É, Nagymihály Z, Both EB, Lambert N, Özvegy-Laczka C, Poór M.   +7 more
europepmc   +1 more source

Chemical disruption of placental thyroid hormone signalling: a systematic review that highlights sex-specific effects. [PDF]

Arch Toxicol
Swan J, Zhurenko D, Huttunen KM, Rysä J.   +3 more
europepmc   +1 more source