Results 11 to 20 of about 1,257 (114)
SEMASEARCH Study Design: Real-World Evaluation of Semaglutide 2.4 mg in Adults With Severe Obesity Underrepresented in Clinical Trials. [PDF]
ABSTRACT Background Although semaglutide 2.4 mg has demonstrated significant weight loss efficacy in clinical trials, real‐world data, particularly with regard to clinically complex and underrepresented populations, remain limited. Objectives The study aims to assess the real‐world effectiveness and patient‐reported outcomes associated with the use of ...
Bel Lassen P +20 more
europepmc +2 more sources
Abstract This study investigates the ex‐ante effects of the front‐of‐package (FoP) nutrition labeling for food products high in saturated fat, sugar, and/or sodium, which is a new regulation recently announced by Health Canada to combat obesity. The Canadian food industry has until January 1, 2026, to comply with the new regulations.
Yu Na Lee +3 more
wiley +1 more source
Summary Worldwide, obesity almost tripled between 1975 and 2016 and is now prevalent in both rich and poor countries. Using annual food availability data produced by the Food and Agriculture Organisation of the United Nations (FAO) covering half a century in 118 countries, this article explores the diets that are central to the problem of obesity ...
Thai H. Le, Marta Disegna, Tim Lloyd
wiley +1 more source
Costs of the COVID‐19 pandemic associated with obesity in Europe: A health‐care cost model
Summary Excess weight is associated with severe outcomes of coronavirus disease 2019 (COVID‐19). We aimed to estimate the total secondary care costs by body mass index (BMI, kg/m2) category when hospitalized due to COVID‐19 in Europe during the first wave of the pandemic from January to June 2020.
Sebastien Czernichow +8 more
wiley +1 more source
Key Messages The emergence of diabetes in this community was tied to cultural change and was a by‐product of colonization. Historical economic development had unintended health consequences for Canada's northern Indigenous people. The epidemiologic transition played out differently for different cohorts within the community.
Paul Hackett +2 more
wiley +1 more source
Nutritional and functional outcomes in trials of nutrient-stimulated hormone-based therapy-A systematic mapping review. [PDF]
Summary Introduction Currently, trials are investigating the efficacy of nutrient‐stimulated hormone‐based therapies (NuSHs) in promoting weight loss in people living with overweight and obesity. However, the extent to which nutritional and functional outcomes are evaluated remains uncertain.
Czernichow S +5 more
europepmc +2 more sources
Six Years of Genetic Diagnosis of Severe Early-Onset Obesity in a French Cohort. [PDF]
ABSTRACT Objective Obesity is a multifactorial disease with a strong genetic component. It is imperative to enhance the identification of genetic variations in their early and severe manifestations in order to facilitate the development of personalized therapeutic strategies, informed clinical care, and the facilitation of genetic counseling.
Rama M +12 more
europepmc +2 more sources
Comparative Study of PPARγ Targets in Human Extravillous and Villous Cytotrophoblasts
Trophoblasts, as the cells that make up the main part of the placenta, undergo cell differentiation processes such as invasion, migration, and fusion. Abnormalities in these processes can lead to a series of gestational diseases whose underlying mechanisms are still unclear.
Fulin Liu +7 more
wiley +1 more source
La transplantation rénale (TR) constitue le traitement de choix de l'insuffisance rénale chronique terminale. Les complications métaboliques après TR (diabète, dyslipidémie, hyperuricémie, obésité), en grande partie liées au traitement immunosuppresseur,
Hala Mouram +4 more
doaj +1 more source
Adipokines : rôle dans l’obésité et l’insulino‐résistance
Le tissu adipeux longtemps considéré comme un organe de stockage est maintenant reconnu comme un organe endocrine. Cette revue étudie l’action de 3 adipokines sécrétées par le tissu adipeux et impliquées dans le contrôle de l’homéostasie énergétique et l’
Aubert Roberte
doaj +1 more source

