Results 1 to 10 of about 825,693 (259)

Aglycemic growth enhances carbohydrate metabolism and induces sensitivity to menadione in cultured tumor-derived cells

Cancer & Metabolism, 2021
Background Hepatocellular carcinoma (HCC) is the most prevalent form of liver malignancy and carries poor prognoses due to late presentation of symptoms.
Cameron A. Schmidt, Kelsey L. McLaughlin, Ilya N. Boykov, Rafiq Mojalagbe, Arthi Ranganathan, Katherine A. Buddo, Chien-Te Lin, Kelsey H. Fisher-Wellman, P. Darrell Neufer   +8 more
doaj   +1 more source

Diabetic ketoacidosis as first presentation of latent autoimmune diabetes in adults in a patient with hashitoxicosis as first presentation of Hashimoto’s thyroiditis: a case report

Journal of Medical Case Reports, 2022
Background Latent autoimmune diabetes in adults is an infrequent form of autoimmune diabetes mellitus, while Hashimoto’s thyroiditis, the most common thyroid disease in adults, rarely manifests as thyrotoxicosis.
Maria Xenou, Ioannis Zoupas, Dimitrios Lygnos, Evangelos Fousteris   +3 more
doaj   +1 more source

To Be or Not To Be—Obese [PDF]

Endocrinology, 2011
The prevalence of obesity in westernized societies is now considered by epidemiologists to be at an epidemic level. Slightly over a third of adult Americans are considered obese because they have a body mass index of more than 30 kg/m2 (1). Additionally, the percentage of the U.S.
Josephine M. Egan, Stuart Maudsley, Bronwen Martin   +2 more
openaire   +3 more sources

The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue

Nature Communications, 2021
Chlorpyrifos is a widely-used pesticide and a common residue on vegetables and fruits. Here the authors show that at non-neurotoxic doses, chlorpyrifos reduces energy expenditure, by inhibiting diet induced thermogenesis, and promotes obesity and insulin
Bo Wang, Evangelia E. Tsakiridis, Shuman Zhang, Andrea Llanos, Eric M. Desjardins, Julian M. Yabut, Alexander E. Green, Emily A. Day, Brennan K. Smith, James S. V. Lally, Jianhan Wu, Amogelang R. Raphenya, Krishna A. Srinivasan, Andrew G. McArthur, Shingo Kajimura, Jagdish Suresh Patel, Michael G. Wade, Katherine M. Morrison, Alison C. Holloway, Gregory R. Steinberg   +19 more
doaj   +1 more source

Association between hepatic steatosis and fibrosis with measures of insulin sensitivity in patients with severe obesity and type 2 diabetes - a cross-sectional study

BMC Gastroenterology, 2022
Background Obesity, non-alcoholic fatty liver disease (NAFLD) and insulin resistance are three pathological conditions highly correlated, but this relationship is not fully elucidated.
Kathrine Aglen Seeberg, Dag Hofsø, Heidi Borgeraas, John Olav Grimnes, Farhat Fatima, Lars Thomas Seeberg, Nils Petter Kvan, Marius Svanevik, Jens Kristoffer Hertel, Jøran Hjelmesæth   +9 more
doaj   +1 more source

Childhood obesity [PDF]

BMJ, 2006
Obesity, an excessive body fat content with increased risk of morbidity, has become increasingly common in children and adolescents. Confusion exists, however, over basic questions such as whether paediatric obesity matters, how to diagnose it, and whether it should be treated (and if so, how best to do this).
Reilly, J. J, Wilson, D.
openaire   +4 more sources

Preventing White Adipocyte Browning during Differentiation In Vitro: The Effect of Differentiation Protocols on Metabolic and Mitochondrial Phenotypes

Stem Cells International, 2022
Mitochondrial dysfunction in white adipose tissue is strongly associated with obesity and its metabolic complications, which are important health challenges worldwide.
Elena Herbers, Mimmi Patrikoski, Anita Wagner, Riikka Jokinen, Antti Hassinen, Sini Heinonen, Susanna Miettinen, Hilkka Peltoniemi, Eija Pirinen, Kirsi H. Pietiläinen   +9 more
doaj   +1 more source

Strengthening resistance to the COVID-19 pandemic and fostering future resilience requires concerted action on obesity

Global Health Action, 2020
Initial observations showed that people with chronic noncommunicable diseases were at heightened risk of severe COVID-19 and adverse outcomes. Subsequently, data from various countries have revealed obesity as an independent and significant factor, with ...
Angela M. Jackson-Morris, Rachel Nugent, Johanna Ralston, Olivia Barata Cavalcanti, John Wilding   +4 more
doaj   +1 more source

Family-Based Telehealth Initiative to Improve Nutrition and Physical Activity for Children With Obesity and Its Utility During COVID-19: A Mixed Methods Evaluation

Frontiers in Nutrition, 2022
Guidelines recommend primary care providers refer children with obesity to behavioral interventions, but given limited program availability, access, and parental engagement, referrals remain rare.
Melissa N. Poulsen, Jennifer Franceschelli Hosterman, G. Craig Wood, Adam Cook, Lyndell Wright, Scott T. Jamieson, Allison Naylor, Shawnee Lutcher, Jacob Mowery, Christopher J. Seiler, Gregory J. Welk, Lisa Bailey-Davis, Lisa Bailey-Davis   +12 more
doaj   +1 more source

Gender-related differences in cardiometabolic risk factors and lifestyle behaviors in treatment-seeking adolescents with severe obesity

BMC Pediatrics, 2018
Background Obesity during adolescence is associated with cardiovascular mortality in adulthood. The adverse obesity-related cardiometabolic risk profile is already observed in adolescence.
Lisa Ha Barstad, Pétur B. Júlíusson, Line Kristin Johnson, Jens Kristoffer Hertel, Samira Lekhal, Jøran Hjelmesæth   +5 more
doaj   +1 more source