Results 71 to 80 of about 1,850 (239)
Obesogens: molecular signaling pathways in fish
* santos@ciimar.up.pt; filipe.castro@ciimar.up.pt In mammals, improper control of lipid metabolism may result in serious health problems such as obesity, increased risk of coronary disease, diabetes and related problems.
Miguel Machado Santos +2 more
doaj +1 more source
Metabolic disrupting effects of polychlorinated biphenyls revealed by long-term temporal variations of lipids in detritivorous fish from the Rio de la Plata Basin [PDF]
The long-term covariation (2002-2017) of lipids, polychlorinated biphenyls (PCBs), and sewage tracers was studied in the detritivorous fish (Prochilodus lineatus) and settling detritus from the Rio de la Plata. Fatty fish from polluted Buenos Aires area (
Colombo, Juan Carlos +3 more
core +1 more source
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt +5 more
wiley +1 more source
The Mammalian "Obesogen" Tributyltin Targets Hepatic Triglyceride Accumulation and the Transcriptional Regulation of Lipid Metabolism in the Liver and Brain of Zebrafish. [PDF]
Recent findings indicate that different Endocrine Disrupting Chemicals (EDCs) interfere with lipid metabolic pathways in mammals and promote fat accumulation, a previously unknown site of action for these compounds.
Angeliki Lyssimachou +9 more
doaj +1 more source
Obesogenic environment and childhood obesity [PDF]
SummaryThe increasing prevalence of obesity in youth has contributed to the growing global burden of chronic diseases (e.g. diabetes, cardiovascular diseases and cancers), which has been largely accounted for by obesogenic behaviours and environments.
openaire +2 more sources
ABSTRACT Introduction Childhood obesity is a public health concern. Studies have investigated the effects of metal mixtures on childhood obesity but none have identified periods of heightened susceptibility of exposure. We identified the periods by investigating the association of metal mixture, measured at four time points, with adiposity.
Janice M. Y. Hu +8 more
wiley +1 more source
Whilst western diet and sedentary lifestyles heavily contribute to the global obesity epidemic, it is likely that chemical exposure may also contribute.
Eren Ozcagli +2 more
doaj +1 more source
Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on the available evidence in relation to the potential obesogenic activity of certain chemical compounds that may be present in foods [PDF]
*This record is given in both English and Spanish According to the World Health Organization (WHO), obesity and overweight have reached epidemic proportions globally.
AESAN Scientific Committee
core +1 more source
ABSTRACT Objectives Nonalcoholic fatty liver disease (NAFLD) is a major public health problem and the most common chronic liver disease today. In Korea, the prevalence and incidence of NAFLD are currently very high, causing a serious social burden. Perfluoroalkyl substances (PFAS) have been consistently implicated as a potential cause of NAFLD, but ...
Jisuk Yun, Young‐Sun Min
wiley +1 more source
Endocrine disrupting chemicals (EDCs) disrupt the physiological metabolism, thus playing an important role in the development of obesity. EDCs, the so-called ‘obesogens’, might predispose some individuals to gain weight.
Sun-Il Choi +5 more
doaj +1 more source

