Results 71 to 80 of about 781 (170)

DEHP deregulates adipokine levels and impairs fatty acid storage in human SGBS-adipocytes

Scientific Reports, 2018
DEHP is a plasticizer which has been used in plastic products of everyday use for decades. Studies in mice and murine cell culture models identified DEHP as an endocrine disruptor that may also act as an obesogen. As this is of high concern in respect of
Kristina Schaedlich, Scarlett Gebauer, Luise Hunger, Laura-Sophie Beier, Holger M. Koch, Martin Wabitsch, Bernd Fischer, Jana Ernst   +7 more
doaj   +1 more source

Environmental Obesogens: What You Need to Know [PDF]

Journal of Advanced Pharmacy Research
Background and Objective: Obesity has evolved into a present-day pandemic, impacting individuals of all ages globally. Various factors have been implicated in the worldwide increase of obesity and diseases related to it, examined from numerous viewpoints.
Malak JABAQJI, Shaimaa NAKAMEH, Ola KABEER, Dima joujeh   +3 more
doaj   +1 more source

Zebrafish obesogenic test: a tool for screening molecules that target adiposity

Journal of Lipid Research, 2011
Dietary and xenobiotic compounds may alter endocrine signaling and lipid homeostasis, thus inducing obesity. We describe a short-term assay method, the zebrafish obesogenic (ZO) test, for examining the effects of diet, drugs, and environmental ...
Angèle Tingaud-Sequeira, Nafia Ouadah, Patrick J. Babin   +2 more
doaj   +1 more source

Triclosan induced obesity via gut microbiota dysbiosis and butyrate reduction

Ecotoxicology and Environmental Safety
Triclosan (TCS) can influence energy metabolism and is a potential obesogen. However, its underlying mechanisms remain largely unknown. This study investigated how low-dose TCS exposure (0.5 mg/kg/day) disrupts energy metabolism in Sprague–Dawley rats ...
Zhen Yu, Jushuang Wu, Junyong Han, Lingmin Wang, Rongmei Lu, Jinyan Chen, Kun Wang, Zhenhua Shi   +7 more
doaj   +1 more source

1,6-Dihydroxynaphthalene as a potential environmental obesogen induces lipid accumulation and liver developmental defects in zebrafish

Ecotoxicology and Environmental Safety
1,6-Dihydroxynaphthalene (1,6-DHN), a key dye intermediate and metabolite of polycyclic aromatic hydrocarbons, may pose environmental endocrine-disrupting risks. However, its toxicological effects remain poorly understood.
Weitao Hu, Wenbin Yuan, Ziang Wang, Ke Xu, Zengyan Di, Yujie Guo, Zhonghao Xiao, Jingrong Tang, Fasheng Liu, Huimin Li, Xiaowen Shi, Shouhua Zhang, Juhua Xiao, Zigang Cao   +13 more
doaj   +1 more source

Obesogenic Environments in Youth

American Journal of Preventive Medicine, 2012
To effectively prevent and reduce childhood obesity through healthy community design, it is essential to understand which neighborhood environment features influence weight gain in various age groups. However, most neighborhood environment research is cross-sectional, focuses on adults, and is often carried out in small, nongeneralizable geographic ...
Janne, Boone-Heinonen, Penny, Gordon-Larsen   +1 more
openaire   +3 more sources

Obesogenic effects of perinatal bisphenol AF exposure on prepubertal male offspring rats

Shanghai yufang yixue
ObjectiveTo investigate the disruptive effects of perinatal exposure to the environmental endocrine disruptor bisphenol AF (BPAF) on hepatic lipid metabolism in prepubertal (postnatal day 21, PND21) male offspring rats, and to provide scientific evidence
LIU Xi, YANG Zhengli, CHENG Xueqing, YANG Jun, XU Jing, HONG Xinyu   +5 more
doaj   +1 more source

The 2R, 3R isomer of 2, 3-butanediol prevents weight gain and decreases plasma glucose concentration of mice fed a fat-enriched diet

Frontiers in Physiology
BackgroundWe have previously shown that, in comparison with wild-type mice, mice that lack a functional flavin-containing monooxygenase 5 gene (Fmo5-/- mice) exhibit reduced weight gain as they age, reduced fat deposition, and lower plasma concentrations
Sunil Veeravalli, Toryn M. Poolman, Jeremy R. Everett, Ian R. Phillips, Ian R. Phillips, Elizabeth A. Shephard   +5 more
doaj   +1 more source

Obesogens in Adolescence: Challenging Aspects and Prevention Strategies

Children
Childhood obesity has become a global epidemic, with significant increases in prevalence over recent decades. While excessive calorie consumption and physical inactivity are known factors, emerging research highlights the role of endocrine-disrupting ...
Marina Nicolaou, Meropi Toumba, Alexandros Kythreotis, Habib Daher, Nicos Skordis   +4 more
doaj   +1 more source

Maternal nanoplastic ingestion induces an increase in offspring body weight through altered lipid species and microbiota

Environment International
The rapidly increasing prevalence of obesity and overweight, especially in children and adolescents, has become a serious societal issue. Although various genetic and environmental risk factors for pediatric obesity and overweight have been identified ...
Bohyeon Jeong, Ji-Sun Kim, A Ra Kwon, Jangjae Lee, Subin Park, Jahong Koo, Wang Sik Lee, Jeong Yeob Baek, Won-Ho Shin, Jung-Sook Lee, Jinyoung Jeong, Won Kon Kim, Cho-Rok Jung, Nam-Soon Kim, Sung-Hee Cho, Da Yong Lee   +15 more
doaj   +1 more source