Results 61 to 70 of about 781 (170)

A national survey of iodine nutrition in children aged 3–6 years in China and its relationship with children's physical growth

Maternal &Child Nutrition, Volume 20, Issue 4, October 2024.
This study highlights the iodine nutritional status among Chinese children aged 3–6 years, revealing that while levels are generally adequate. Our findings stress the importance of tailored iodine supplementation to support optimal health and development in preschoolers.
Jing Li, Jun‐Xia Liu, Xiao‐Li Shen, Yu‐Qing Wang, Chong‐Huai Yan   +4 more
wiley   +1 more source

Trapped fat: Obesity pathogenesis as an intrinsic disorder in metabolic fuel partitioning

Obesity Reviews, Volume 25, Issue 10, October 2024.
Summary Our understanding of the pathophysiology of obesity remains at best incomplete despite a century of research. During this time, two alternative perspectives have helped shape thinking about the etiology of the disorder. The currently prevailing view holds that excessive fat accumulation results because energy intake exceeds energy expenditure ...
Mark I. Friedman, Thorkild I. A. Sørensen, Gary Taubes, Jens Lund, David S. Ludwig   +4 more
wiley   +1 more source

Metabolic disrupting chemicals in the intestine: the need for biologically relevant models

FEBS Open Bio, Volume 14, Issue 9, Page 1397-1419, September 2024.
In this review, we aimed to study how the intestine may be disrupted by metabolic endocrine disruptors (MDCs) both in its own metabolism and in its relationships with other organs. Zebrafish shares numerous similarities with human gastrointestinal tract, representing an opportunity to study the complex interactions of MDCs at the intestinal level and ...
Chedi Erradhouani, Sylvie Bortoli, Selim Aït‐Aïssa, Xavier Coumoul, François Brion   +4 more
wiley   +1 more source

An optimized zebrafish obesogenic test protocol with an artificial intelligence-based analysis software for screening obesogens and anti-obesogens

Biology Methods and Protocols
Abstract Obesity is defined as a disease in which abnormal excessive body fat accumulation causes adverse effects on health. One proposed contributing factor to the rise in obesity is the exposure to endocrine disruptors acting as obesogens.
Al Kassir, Sara, Mercé, Théo, Pedemay, Sandra, M Bourcier, Laure, Soares, Magalie, Le Mentec, Hélène, Podechard, Normand, Knoll-Gellida, Anja, Babin, Patrick J.   +8 more
openaire   +4 more sources

Associations between paediatric obesity, chemical mixtures and environmental factors, in a national cross‐sectional study of Canadian children

Pediatric Obesity, Volume 19, Issue 8, August 2024.
Summary Background Whilst single chemical exposures are suspected to be obesogenic, the combined role of chemical mixtures in paediatric obesity is not well understood. Objectives We aimed to evaluate the potential associations between chemical mixtures and obesity in a population‐based sample of Canadian children.
Rose Dugandzic, Natalia Konstantelos, Yamei Yu, Eric Lavigne, Sebastian Srugo, Justin J. Lang, Kristian Larsen, Tyler Pollock, Paul Villeneuve, Errol M. Thomson, Miranda MacPherson, Robert Dales, Sabit Cakmak   +12 more
wiley   +1 more source

The endocrine disruptor mono-(2-ethylhexyl)phthalate promotes adipocyte differentiation and induces obesity in mice

Bioscience Reports, 2012
The environmental obesogen hypothesis proposes that exposure to endocrine disruptors during developmental ‘window’ contributes to adipogenesis and the development of obesity.
Chanjuan Hao, Xuejia Cheng, Hongfei Xia, Xu Ma   +3 more
doaj   +1 more source

Triphenyl phosphate induces lipid metabolism disorder and promotes obesity through PI3K/AKT signaling pathway

Environment International
Triphenyl phosphate (TPHP) is a widely used organic phosphate flame retardant that has been reported as a potential environmental obesogen. However, the potential impact and mechanism of action of TPHP on adipose tissue are still unclear.
Tianlan Li, Yiwa Liu, Jingyi Cao, Xianzhu Lu, Yinghan Lu, Yuhan Wang, Chunmei Zhang, Meifen Wu, Song Deng, Li Li, Ming Shi   +10 more
doaj   +1 more source

Estrogens counteract tributyltin-induced toxicity in the rat islets of Langerhans

Heliyon, 2020
Background: Tributyltin (TBT) is known as an endocrine disruptor able to interfere with estrogen receptors (ERs) leading to toxic effects on the related endocrine pathways.
Faezeh Ghaemmaleki, Perham Mohammadi, Maryam Baeeri, Mona Navaei-Nigjeh, Mohammad Abdollahi, Sara Mostafalou   +5 more
doaj   +1 more source

Exposure to 4,4′‐DDE in visceral adipose tissue and weight loss in adolescents from the Teen‐LABS cohort

Obesity, Volume 32, Issue 5, Page 1023-1032, May 2024.
Abstract Objective Dichlorodiphenyldichloroethylene (DDE), an obesogen accumulating in adipose tissue, is released into circulation with weight loss, although its impact is underexplored among adolescents. We tested the association using an integrative translational approach of epidemiological analysis among adolescents with obesity and in vitro ...
Bruna Rubbo, Zhenjiang Li, Phum Tachachartvanich, Brittney O. Baumert, Hongxu Wang, Shudi Pan, Sarah Rock, Justin R. Ryder, Todd Jenkins, Stephanie Sisley, Xiangping Lin, Scott Bartell, Thomas H. Inge, Stavra Xanthakos, Brooklynn McNeil, Anna R. Robuck, Michele A. La Merrill, Douglas I. Walker, David V. Conti, Rob McConnell, Sandrah P. Eckel, Lida Chatzi   +21 more
wiley   +1 more source

Unique Perspectives on the Obesogenic Environment [PDF]

Journal of General Internal Medicine, 2007
We all live in an obesogenic environment. 1 The availability of high energy dense, palatable, inexpensive food is only surpassed by the mechanized labor-saving and entertainment devices designed to keep us from moving too much. We have evolved from a society of hunter–gatherers to a society of drivethrough picker-uppers.
openaire   +2 more sources