Results 41 to 50 of about 1,850 (239)

Endocrine disrupters as obesogens [PDF]

Molecular and Cellular Endocrinology, 2009
The recent dramatic rise in obesity rates is an alarming global health trend that consumes an ever increasing portion of health care budgets in Western countries. The root cause of obesity is thought to be a prolonged positive energy balance. Hence, the major focus of preventative programs for obesity has been to target overeating and inadequate ...
Felix, Grün, Bruce, Blumberg
openaire   +2 more sources

Role of Obesogens in the Pathogenesis of Obesity [PDF]

Medicina, 2019
Obesity is considered to be a 20th century pandemic, and its prevalence correlates with the increasing global pollution and the presence of chemical compounds in the environment. Excessive adiposity results from an imbalance between energy intake and expenditure, but it is not merely an effect of overeating and lack of physical activity.
Urszula Shahnazaryan, Marta Wójcik, Tomasz Bednarczuk, Alina Kuryłowicz   +3 more
openalex   +4 more sources

Minireview: The Case for Obesogens [PDF]

Molecular Endocrinology, 2009
AbstractObesity and obesity-related disorders, such as type 2 diabetes, hypertension, and cardiovascular disease, are epidemic in Western countries, particularly the United States. The conventional wisdom holds that obesity is primarily the result of a positive energy balance, i.e. too many calories in and too few calories burned.
Felix, Grün, Bruce, Blumberg
openaire   +2 more sources

Endocrine disruptors and obesity [PDF]

, 2017
The purpose of this review is to summarise current evidence that some environmental chemicals may be able to interfere in endocrine regulation of energy metabolism and adipose tissue structure.
A Janesick, A Janesick, A Pereira-Fernandes, AM Calafat, AV Krishnan, BS Rubin, C Koebrick, C Power, CH Hurst, D Hanahan, D Pugazhendhi, E Oken, EC Dodds, ED Rosen, EE Hatch, EE Kershaw, EK Maloney, F Ariemma, F Grun, F Grün, FS Saal vom, G Williams, GAS Ansari, GM Cooke, GM Lehmann, H Inadera, H Masuno, H Masuno, HB Patisaul, HK Kim, J Haarbo, J Kim, J Law, J Wu, JG Boucher, JL Tang-Peronard, JN Feige, JR Rochester, KL Spalding, L Bramwell, L Yin, LN Vandenberg, M Bastien, M LaMerrill, M Penza, M Saitoh, M Vafeiadi, MA Kamrin, MJ Silva, ML Silva da, NA Berger, NCEP ATP-III, OW Smith, P Ferre, P Hu, P Tontonoz, PC Huang, PD Darbre, R White, RL Ruhlen, RM Harris, RR Newbold, RR Newbold, RR Newbold, RR Newbold, RR Newbold, RW Stahlhut, S Hallgren, S Kirchner, SA Ross, SA Whitehead, SJ Oppeneer, SL Verhulst, T Horiguchi, T Kanayama, V Arsenescu, X Li, X Li, Y Zhang   +78 more
core   +1 more source

Parma consensus statement on metabolic disruptors [PDF]

, 2015
A multidisciplinary group of experts gathered in Parma Italy for a workshop hosted by the University of Parma, May 16–18, 2014 to address concerns about the potential relationship between environmental metabolic disrupting chemicals, obesity and related ...
A Janesick, A Janesick, A Mantovani, Alberto Mantovani, Alexander Suvorov, Barbara A. Cohn, BM Angle, Bruce Blumberg, C Anacker, C Casals-Casas, C Hao, C Hao, Christopher Kassotis, CL Ogden, D Dabelea, D Valvi, E Somm, EE Hatch, Elena Fabbri, EP Hines, F Grun, Frederick S. vom Saal, Gemma Calamandrei, Giancarlo Panzica, Giorgio Sartor, Graziano Ceresini, H Mackay, IA Lang, J Wei, Jerrold J. Heindel, JJ Heindel, JL Bolton, JL Tang-Peronard, JP Burke, JP Despres, JR McCarrey, Juliette Legler, Jérôme Ruzzin, L Trasande, L Trasande, Laura Gioiosa, Laura Molteni, Laura Rizzir, Luisa Montanini, M Manikkam, M Merrill La, M Merrill La, M Merrill La, MA Hanson, Maria E. Street, Michele La Merrill, Michelle A. Mendez, MK Skinner, MK Skinner, MK Skinner, P Amuna, Paola Palanza, Patrizia Bovolin, R Chamorro-Garcia, R Tracey, R. Thomas Zoeller, Riccardo Volpi, Ronit Machtinger, RR Newbold, RR Newbold, RT Zoeller, RW Stahlhut, S O’Neill, Silvia Paterlini, SM Belcher, SM Snedeker, Stefano Parmigiani, Susan C. Nagel, Thaddeus T. Schug, Valentina Pomatto, YC Klimentidis   +75 more
core   +5 more sources

Expression of obesity markers and Persistent Organic Pollutants levels in adipose tissue of obese patients: reinforcing the obesogen hypothesis? [PDF]

PLoS ONE, 2014
Persistent Organic Pollutants (POPs) accumulate in adipose tissue and some are described to possess endocrine disrupting capacities. Therefore, it is important to evaluate their effects on key endocrine pathways in adipose tissue (AT), to further ...
Anna Pereira-Fernandes, Eveline Dirinck, Alin C Dirtu, Govindan Malarvannan, Adrian Covaci, Luc Van Gaal, Caroline Vanparys, Philippe G Jorens, Ronny Blust   +8 more
doaj   +1 more source

Traffic-related air pollution and obesity formation in children: a longitudinal, multilevel analysis. [PDF]

, 2014
BackgroundBiologically plausible mechanisms link traffic-related air pollution to metabolic disorders and potentially to obesity. Here we sought to determine whether traffic density and traffic-related air pollution were positively associated with growth
Berhane, Kiros, Chang, Roger, Dunton, Genevieve, Gilliland, Frank, Islam, Talat, Jerrett, Michael, Lam, Claudia, Lurmann, Fred, McConnell, Rob, Wolch, Jennifer   +9 more
core   +3 more sources

Microbiota analysis for risk assessment of xenobiotic exposure and the impact on dysbiosis: identifying potential next‐generation probiotics

EFSA Journal, Volume 21, Issue S1, November 2023., 2023
Abstract On‐going projects of the team are currently dealing with microbiota, xenobiotics, endocrine‐disrupting chemicals (EDCs), obesity, inflammation and probiotics. The combination of diet, lifestyle and the exposure to dietary xenobiotics categorised into microbiota‐disrupting chemicals (MDCs) could determine obesogenic‐related dysbiosis.
Ana López‐Moreno, Philippe Langella, Rebeca Martín, Margarita Aguilera   +3 more
wiley   +1 more source

Mercury Exposure and Associations with Hyperlipidemia and Elevated Liver Enzymes: A Nationwide Cross-Sectional Survey

Toxics, 2020
Mercury (Hg) has obesogenic properties. However, the associated health outcomes of population-level mercury exposure were unclear. This study investigated the relationships between blood mercury levels and obesity-related outcomes such as hyperlipidemia ...
Seungho Lee, Sung-Ran Cho, Inchul Jeong, Jae Bum Park, Mi-Yeon Shin, Sungkyoon Kim, Jin Hee Kim   +6 more
doaj   +1 more source

Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect. [PDF]

PLoS ONE, 2013
Recently the environmental obesogen hypothesis has been formulated, proposing a role for endocrine disrupting compounds (EDCs) in the development of obesity. To evaluate this hypothesis, a screening system for obesogenic compounds is urgently needed.
Anna Pereira-Fernandes, Heidi Demaegdt, Karine Vandermeiren, Tine L M Hectors, Philippe G Jorens, Ronny Blust, Caroline Vanparys   +6 more
doaj   +1 more source