Results 51 to 60 of about 618,864 (388)

An ethical issue: nurses’ conscientious objection regarding induced abortion in South Korea

open access: yesBMC Medical Ethics, 2020
Background The Constitutional Court of South Korea declared that an abortion ban was unconstitutional on April 11, 2019. The National Health Care System will provide abortion care across the country as a formal medical service. Conscientious objection is
Chung Mee Ko, Chin Kang Koh, Ye Sol Lee
doaj   +1 more source

Epistemic Schmagency? [PDF]

open access: yes, 2018
Constructivist approaches in epistemology and ethics offer a promising account of normativity. But constructivism faces a powerful Schmagency Objection, raised by David Enoch.
Flowerree, A. K.
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Arap Dilinde Kıyâs Meʿa’l-Fârık

open access: yesTokat İlmiyat Dergisi
Nahiv usûlü ilminde dilde ortak illet nedeniyle menkûl olmayanı (makîs/ferʿ) menkûl olana (makîsun aleyh/asl) hamletmek olarak tanımlan kıyas, hem mütekaddim hem de müteahhir nahiv âlimleri tarafından vazgeçilmez bir yöntem olarak ele alınmıştır.
Abdulkadir Kişmir
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Providing of public services in the field of biomedicine [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2018
The paper analyzes one of the new notions in Serbian administrative law, created by the Law on General Administrative Procedure - providing of public services.
Radošević Ratko S.
doaj  

Abandonment of abstract personal status rights -Study comparison- [PDF]

open access: yesالرافدین للحقوق
Rights are numerous and diverse, and a person's life is never devoid of rights either granted to them or imposed upon them. Among the most significant principles related to rights is the concept of substitution and settlement, particularly in light of ...
Mohammad Alhasso
doaj   +1 more source

Pluralism about Knowledge [PDF]

open access: yes, 2017
In this paper I consider the prospects for pluralism about knowledge, that is, the view that there is a plurality of knowledge relations. After a brief overview of some views that entail a sort of pluralism about knowledge, I focus on a particular kind ...
Berit Brogaard   +34 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

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